Paralogue Annotation for RYR2 residue 1366

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1366
Reference Amino Acid: T - Threonine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 1366

No paralogue variants have been mapped to residue 1366 for RYR2.

RYR2	DYDADSDFEVLMKTAHGHLVPDRVDKDKEA>T<KPEFNNHK--------------DYAQEKP-	1381
RYR1	AAEPDPDYENLRRSAGGWSEAENGKEGTAK>E<GAPGGTPQAGGEAQPARAENEKDATTEKNK	1384
RYR3	------------------------------>-<------------------------------
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T1366A	c.4096A>G	Putative Benign		rs369982130	SIFT: tolerated Polyphen: benign
p.T1366N	c.4097C>A	Putative Benign			SIFT: tolerated Polyphen: benign