Paralogue Annotation for RYR2 residue 1425

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1425
Reference Amino Acid: T - Threonine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 1425

No paralogue variants have been mapped to residue 1425 for RYR2.



RYR2DYSTSHSARLTEDVLADDRDDYDFLMQT-S>T<YYYSVRIFPGQEPANVWVGWITSDFHQYDT1455
RYR1PPATPTLPRLPHDVVPADNRDDPEIILNTT>T<YYYSVRVFAGQEPSCVWAGWVTPDYHQHDM1461
RYR3------SPCLDSEAFQKRKQMQEILSHTTT>Q<CYYAIRIFAGQDPSCVWVGWVTPDYHLYSE1357
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T1425Ac.4273A>G Putative BenignSIFT:
Polyphen:
p.T1425Mc.4274C>T Putative BenignSIFT:
Polyphen: