Paralogue Annotation for RYR2 residue 1845

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1845
Reference Amino Acid: L - Leucine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 1845

No paralogue variants have been mapped to residue 1845 for RYR2.



RYR2EFLFVPLIKLFYTLLIMGIFHNEDLKHILQ>L<IEPSVFKEAATPEEESDTL--E-K---ELS1869
RYR1EFQFVPVLKLVSTLLVMGIFGDEDVKQILK>M<IEPEVFTEEEEEEDEEEEGEEEDEEEKEED1895
RYR3EFQFVPVLKLIGTLLVMGVFDDDDVRQILL>L<IDPSVFGEHSAGTEEGAEK--E-E---VTQ1773
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.L1845Fc.5535G>T Putative BenignSIFT:
Polyphen: