Paralogue Annotation for RYR2 residue 1863

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1863
Reference Amino Acid: T - Threonine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 1863

No paralogue variants have been mapped to residue 1863 for RYR2.

RYR2	IFHNEDLKHILQLIEPSVFKEAATPEEESD>T<L--E-K---ELS----VDDAK-LQGAGEE-	1881
RYR1	IFGDEDVKQILKMIEPEVFTEEEEEEDEEE>E<GEEEDEEEKEEDEEETAQEKEDEEKEEEEA	1913
RYR3	VFDDDDVRQILLLIDPSVFGEHSAGTEEGA>E<K--E-E---VTQ----VEEKA-VEAG----	1782
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.T1863M	c.5588C>T	Putative Benign			SIFT: Polyphen: