Paralogue Annotation for RYR2 residue 1881

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1881
Reference Amino Acid: E - Glutamate
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 1881

No paralogue variants have been mapped to residue 1881 for RYR2.

RYR2	DTL--E-K---ELS----VDDAK-LQGAGE>E<--EAKGGKRPKEGLLQMKLPEPVKLQMCLL	1909
RYR1	EEGEEEDEEEKEEDEEETAQEKEDEEKEEE>E<AAEGEKEEGLEEGLLQMKLPESVKLQMCHL	1942
RYR3	AEK--E-E---VTQ----VEEKA-VEAG-->-<--EKAGKEAPVKGLLQTRLPESVKLQMCEL	1810
cons	> <

See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.E1881K	c.5641G>A	Putative Benign			SIFT: Polyphen: