Paralogue Annotation for RYR2 residue 1941

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 1941
Reference Amino Acid: R - Arginine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 1941

No paralogue variants have been mapped to residue 1941 for RYR2.



RYR2QYLCDCQVRHRIEAIVAFSDDFVAKLQDNQ>R<FRYNEVMQALNMSAALTARKTKEFRSPPQE1971
RYR1EYFCDQELQHRVESLAAFAERYVDKLQANQ>R<SRYGLLIKAFSMTAAETARRTREFRSPPQE2004
RYR3SYLCDCELQHRVEAIVAFGDIYVSKLQANQ>K<FRYNELMQALNMSAALTARKTKEFRSPPQE1872
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R1941Hc.5822G>A Putative BenignSIFT: tolerated
Polyphen: probably damaging
p.R1941Cc.5821C>T Putative BenignSIFT:
Polyphen:
p.R1941Sc.5821C>A Putative BenignSIFT:
Polyphen: