Paralogue Annotation for RYR2 residue 235

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 235
Reference Amino Acid: R - Arginine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 235

No paralogue variants have been mapped to residue 235 for RYR2.



RYR2AAFQQTLWSVAPISSGSEAAQGYLIGGDVL>R<LLHGHMDECLTVPSGEHGEEQRRTVHYEGG265
RYR1ASFMQTLWNMNPICSR--CEEGFVTGGHVL>R<LFHGHMDECLTISPAD-SDDQRRLVYYEGG249
RYR3ASFMQTLWNVHPTCSGSSIEEGYLLGGHVV>R<LFHGH-DECLTIPSTDQNDSQHRRIFYEAG254
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Arg235Lysc.704G>A UnknownSIFT:
Polyphen: