Paralogue Annotation for RYR2 residue 2485

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 2485
Reference Amino Acid: L - Leucine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 2485

No paralogue variants have been mapped to residue 2485 for RYR2.



RYR2DMSAGFCPDHKAAMVLFLDRVYGIEVQDFL>L<HLLEVGFLPDLRAAASLDTAALSATDMALA2515
RYR1KMSASFVPDHKASMVLFLDRVYGIENQDFL>L<HVLDVGFLPDMRAAASLDTATFSTTEMALA2549
RYR3DMAANFCPDHKAPMVLFLDRVYGIKDQTFL>L<HLLEVGFLPDLRASASLDTVSLSTTEAALA2412
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.L2485Fc.7453C>T Putative BenignSIFT:
Polyphen: