Paralogue Annotation for RYR2 residue 257

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 257
Reference Amino Acid: R - Arginine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 257

No paralogue variants have been mapped to residue 257 for RYR2.



RYR2YLIGGDVLRLLHGHMDECLTVPSGEHGEEQ>R<RTVHYEGGAVSVHARSLWRLETLRVAWSGS287
RYR1FVTGGHVLRLFHGHMDECLTISPAD-SDDQ>R<RLVYYEGGAVCTHARSLWRLEPLRISWSGS271
RYR3YLLGGHVVRLFHGH-DECLTIPSTDQNDSQ>H<RRIFYEAGGAGTRARSLWRVEPLRISWSGS276
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R257Wc.769C>T Putative BenignSIFT:
Polyphen: