Paralogue Annotation for RYR2 residue 2781

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 2781
Reference Amino Acid: T - Threonine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 2781

No paralogue variants have been mapped to residue 2781 for RYR2.



RYR2SKVQPLMKPYKLLSEKEKEIYRWPIKESLK>T<MLAWGWRIERTREGDSMALYNRTRRISQTS2811
RYR1LKTHPMLRPYKTFSEKDKEIYRWPIKESLK>A<MIAWEWTIEKAREGEEEK--TEKKKTRKIS2843
RYR3VKTHPLIRPFKTLTEKEKEIYRWPARESLK>T<MLAVGWTVERTKEGEALVQQRENEKLRSVS2708
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T2781Ic.8342C>T Putative BenignSIFT: deleterious
Polyphen: probably damaging
p.Thr2781Serc.8342C>G UnknownSIFT:
Polyphen: