Paralogue Annotation for RYR2 residue 3398

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 3398
Reference Amino Acid: M - Methionine
Protein Domain: Cytoplasmic region

Paralogue Variants mapped to RYR2 residue 3398

No paralogue variants have been mapped to residue 3398 for RYR2.

RYR2	AFYPLLIRFVDYNRAKWLKEPNPEAEELFR>M<VAEVFIYWSKSHNFKREEQNFVVQNEINNM	3428
RYR1	ALYPLLIRYVDNNRAQWLTEPNPSAEELFR>M<VGEIFIYWSKSHNFKREEQNFVVQNEINNM	3467
RYR3	AFYPMLIRYVDNNRSNWLKSPDADSDQLFR>M<VAEVFILWCKSHNFKREEQNFVIQNEINNL	3324
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See full Alignment of Paralogues

Known Variants in RYR2

Protein	CDS	Disease Classification	Disease	dbSNP links	Effect Prediction
p.M3398L	c.10192A>T	Putative Benign			SIFT: tolerated Polyphen: probably damaging