Paralogue Annotation for RYR2 residue 3508

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 3508
Reference Amino Acid: I - Isoleucine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 3508

No paralogue variants have been mapped to residue 3508 for RYR2.



RYR2LNICAPGDQELIALAKNRFSLKDTEDEVRD>I<IRSNIHLQGKLE-DPAIRWQMALYKDLPNR3537
RYR1LNMCAPTDQDLITLAKTRYALKDTDEEVRE>F<LHNNLHLQGKVEGSPSLRWQMALYRGVPGR3582
RYR3LNMCTPGDQELISLAKSRYSHRDTDEEVRE>H<LRNNLHLQEKSD-DPAVKWQLNLYKDVLK-3437
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.I3508Tc.10523T>C Putative BenignSIFT: deleterious
Polyphen: benign
p.I3508Vc.10522A>G Putative BenignSIFT:
Polyphen: