Paralogue Annotation for RYR2 residue 3736

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 3736
Reference Amino Acid: A - Alanine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 3736

No paralogue variants have been mapped to residue 3736 for RYR2.



RYR2GEEE-VKSFEEKEMEKQKLLYQQARLHDRG>A<AEMVLQTISASKGETGPMVAATLKLGIAIL3766
RYR1AEEEVEVSFEEKQMEKQRLLYQQARLHTRG>A<AEMVLQMISACKGETGAMVSSTLKLGISIL3804
RYR3EDEDKEKTFEEKEMEKQKTLYQQARLHERG>A<AEMVLQMISASKGEMSPMVVETLKLGIAIL3656
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.A3736Tc.11206G>A Putative Benignrs375095599SIFT: deleterious
Polyphen: probably damaging