Paralogue Annotation for RYR2 residue 3963

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 3963
Reference Amino Acid: S - Serine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 3963

No paralogue variants have been mapped to residue 3963 for RYR2.



RYR2QSLAHSRLWDAVVGFLHVFAHMQMKLSQDS>S<QIELLKELMDLQKDMVVMLLSMLEGNVVNG3993
RYR1QSLAHSRLWDAVVGFLHVFAHMMMKLAQDS>S<QIELLKELLDLQKDMVVMLLSLLEGNVVNG4037
RYR3QSLAHSRLWDAVVGFLHVFANMQMKLSQDS>S<QIELLKELLDLLQDMVVMLLSLLEGNVVNG3889
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.S3963Cc.11887A>T Putative BenignSIFT:
Polyphen: