Paralogue Annotation for RYR2 residue 4176

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4176
Reference Amino Acid: V - Valine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 4176

No paralogue variants have been mapped to residue 4176 for RYR2.



RYR2ERVYFEISESSRTQWEKPQVKESKRQFIFD>V<VNEGGEKEKMELFVNFCEDTIFEMQLAAQI4206
RYR1ERIYFEISETNRAQWEMPQVKESKRQFIFD>V<VNEGGEAEKMELFVSFCEDTIFEMQIAAQI4250
RYR3ERVYFEISESSRTQWEKPQVKESKRQFIFD>V<VNEGGEQEKMELFVNFCEDTIFEMQLASQI4102
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Val4176Metc.12526G>A UnknownSIFT:
Polyphen: