Paralogue Annotation for RYR2 residue 4180

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4180
Reference Amino Acid: G - Glycine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 4180

No paralogue variants have been mapped to residue 4180 for RYR2.



RYR2FEISESSRTQWEKPQVKESKRQFIFDVVNE>G<GEKEKMELFVNFCEDTIFEMQLAAQISESD4210
RYR1FEISETNRAQWEMPQVKESKRQFIFDVVNE>G<GEAEKMELFVSFCEDTIFEMQIAAQISEPE4254
RYR3FEISESSRTQWEKPQVKESKRQFIFDVVNE>G<GEQEKMELFVNFCEDTIFEMQLASQISESD4106
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.G4180Rc.12538G>C Putative BenignSIFT:
Polyphen: