Paralogue Annotation for RYR2 residue 4273

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4273
Reference Amino Acid: K - Lysine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 4273

No paralogue variants have been mapped to residue 4273 for RYR2.



RYR2SALFALRYNILTLMRMLSLKSLKKQMKKVK>K<MTVKDMVTAFFSSYWSIFMTLLHFVASVFR4303
RYR1GATARVVAAAGRALRGLSYRSLRRRVRRLR>R<LTAREAATAVAALLWAAVTRAGAAGAGAAA4352
RYR3MACASVKRNVTDFLKRATLKNLRKQYRNVK>K<MTAKELVKVLFSFFWMLFVGLFQLLFTILG4204
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.K4273Ec.12817A>G Putative BenignSIFT:
Polyphen: