Paralogue Annotation for RYR2 residue 4281

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4281
Reference Amino Acid: T - Threonine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 4281

No paralogue variants have been mapped to residue 4281 for RYR2.



RYR2NILTLMRMLSLKSLKKQMKKVKKMTVKDMV>T<AFFSSYWSIFMTLLHFVASVFRGFFRIICS4311
RYR1AAGRALRGLSYRSLRRRVRRLRRLTAREAA>T<AVAALLWAAVTRAGAAGAGAAAGALGLLWG4360
RYR3NVTDFLKRATLKNLRKQYRNVKKMTAKELV>K<VLFSFFWMLFVGLFQLLFTILGGIFQILWS4212
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T4281Mc.12842C>T Putative BenignSIFT: tolerated
Polyphen: benign
p.T4281Sc.12841A>T Putative BenignSIFT:
Polyphen: