Paralogue Annotation for RYR2 residue 4285

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4285
Reference Amino Acid: S - Serine
Protein Domain: Transmembrane region


Paralogue Variants mapped to RYR2 residue 4285

No paralogue variants have been mapped to residue 4285 for RYR2.



RYR2LMRMLSLKSLKKQMKKVKKMTVKDMVTAFF>S<SYWSIFMTLLHFVASVFRGFFRIICSLLLG4315
RYR1ALRGLSYRSLRRRVRRLRRLTAREAATAVA>A<LLWAAVTRAGAAGAGAAAGALGLLWGSLFG4364
RYR3FLKRATLKNLRKQYRNVKKMTAKELVKVLF>S<FFWMLFVGLFQLLFTILGGIFQILWSTVFG4216
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.S4285Lc.12854C>T Putative BenignSIFT:
Polyphen: