Paralogue Annotation for RYR2 residue 4397

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4397
Reference Amino Acid: N - Asparagine
Protein Domain: Transmembrane region


Paralogue Variants mapped to RYR2 residue 4397

No paralogue variants have been mapped to residue 4397 for RYR2.



RYR2ESDLLSD-----IFGLDLKREGGQYKLIPH>N<PNAGLSDLMSN-PVPMPE-V-QEKFQEQ--4422
RYR1EEEAVHEAGPGGADGAVAVTDGGPFRPEGA>G<GLGDMGDTTPAEPPTPEGSP-ILKRKLGVD4481
RYR3DTDIMSD-----LFGLHPKKEGS-LKHGPE>V<GLGDLSEIIGKDEPPTLESTVQKKRKA---4325
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.N4397Kc.13191T>A Putative BenignSIFT:
Polyphen: