Paralogue Annotation for RYR2 residue 4535

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4535
Reference Amino Acid: T - Threonine
Protein Domain: Transmembrane region


Paralogue Variants mapped to RYR2 residue 4535

No paralogue variants have been mapped to residue 4535 for RYR2.



RYR2FAINFILLFYKVSTSSVVEGKE------LP>T<RSSSENAK-VTSLDS-----SSHRIIAVHY4559
RYR1FAINFILLFYKVSDSPPGEDDMEGSAAGDV>S<GAGSGGSSGW-GLGAGEEAEGDEDENMVYY4631
RYR3FAINFILLFYKVTEEPLEEETE------DV>A<NLWN-------SFND-----EEEEEAMVFF4464
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.T4535Mc.13604C>T Putative BenignSIFT:
Polyphen: