Paralogue Annotation for RYR2 residue 4666

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 4666
Reference Amino Acid: I - Isoleucine
Protein Domain: Transmembrane region


Paralogue Variants mapped to RYR2 residue 4666

No paralogue variants have been mapped to residue 4666 for RYR2.



RYR2NTQSFPNNYWDKFVKRKVMDKYGEFYGRDR>I<SELLGMDKAALDFSDAREKKKPKKDSSLSA4696
RYR1NTPSFPSNYWDKFVKRKVLDKHGDIYGRER>I<AELLGMDLATLEITAHNER-KPNPPPGLLT4767
RYR3NTPSFPNNYWDKFVKRKVINKYGDLYGAER>I<AELLGLDKNALDFSPVEET-KA-EAASLVS4599
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.I4666Tc.13997T>C Putative BenignSIFT:
Polyphen: