Paralogue Annotation for RYR2 residue 527

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 527
Reference Amino Acid: K - Lysine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 527

No paralogue variants have been mapped to residue 527 for RYR2.



RYR2LVLECIDRLHVYSSAAHFADVAGREAGESW>K<SILNSLYELLAALIRGNRKNCAQFSGSLDW557
RYR1MVLNCIDRLNVYTTAAHFAEFAGEEAAESW>K<EIVNLLYELLASLIRGNRSNCALFSTNLDW545
RYR3LVLNCIDRLNVYNSVAHFAGIAREESGMAW>K<EILNLLYKLLAALIRGNRNNCAQFSNNLDW544
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.K527Rc.1580A>G Putative BenignSIFT:
Polyphen: