Paralogue Annotation for RYR2 residue 529

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 529
Reference Amino Acid: I - Isoleucine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 529

No paralogue variants have been mapped to residue 529 for RYR2.



RYR2LECIDRLHVYSSAAHFADVAGREAGESWKS>I<LNSLYELLAALIRGNRKNCAQFSGSLDWLI559
RYR1LNCIDRLNVYTTAAHFAEFAGEEAAESWKE>I<VNLLYELLASLIRGNRSNCALFSTNLDWLV547
RYR3LNCIDRLNVYNSVAHFAGIAREESGMAWKE>I<LNLLYKLLAALIRGNRNNCAQFSNNLDWLI546
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.I529Tc.1586T>C Putative BenignSIFT:
Polyphen: