Paralogue Annotation for RYR2 residue 677

Residue details

Gene: RYR2
Reference Sequences: LRG: LRG_402, Ensembl variant: ENST00000366574 / ENSP00000355533
Amino Acid Position: 677
Reference Amino Acid: L - Leucine
Protein Domain: Cytoplasmic region


Paralogue Variants mapped to RYR2 residue 677

No paralogue variants have been mapped to residue 677 for RYR2.



RYR2RLVNHVSSMRPNIFLGVSEGSAQYKKWYYE>L<MVDHTEPFVTAEATHLRVGWASTEGYSPYP707
RYR1NLINYVTSIRPNIFVGRAEGTTQYSKWYFE>V<MVDEVTPFLTAQATHLRVGWALTEGYTPYP695
RYR3RLINDVTSIRPNIFLGVAEGSAQYKKWYFE>L<IIDQVDPFLTAEPTHLRVGWASSSGYAPYP694
cons                              > <                              

See full Alignment of Paralogues


Known Variants in RYR2

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.L677Mc.2029T>A Putative BenignSIFT:
Polyphen: