Paralogue Annotation for SCN5A residue 1088

Residue details

Gene: SCN5A
Reference Sequences: LRG: LRG_289, Ensembl variant: ENST00000333535 / ENSP00000328968
Amino Acid Position: 1088
Reference Amino Acid: A - Alanine
Protein Domain: Interdomain Linker II-III


Paralogue Variants mapped to SCN5A residue 1088

No paralogue variants have been mapped to residue 1088 for SCN5A.



SCN5A--------------------------GGPE>A<P-----PDSRTWSQVSATASS------EA-1106
SCN1A------------------------------>-<------------------------------
SCN2A------------------------------>-<------------------------------
SCN3A------------------------------>-<------------------------------
SCN4A------------------------------>-<------------------------------
SCN7A------------------------------>-<------------------------------
SCN8A------------------------------>-<------------------------------
SCN9A------------------------------>-<------------------------------
SCN10A------------------------------>-<------------------------------
SCN11A------------------------------>-<---------------HQENKK------PT-957
CACNA1ASTTRPIQQDLGRQDPPLAEDIDNMKNNKLA>T<AESAAPHGSLGHAGLPQSPAKMGNSTDPGP1106
CACNA1B------------------------------>-<---EKE--------ATEKEAEIVEADKEKE1017
CACNA1C------------------------------>-<------EMPVGPRP----------------859
CACNA1D------------------------------>-<------EVPAGPRP----------------865
CACNA1E------------------------------>-<--------------MGRVI-------S---1047
CACNA1F------------------------------>-<------EEEGAGGV----------------830
CACNA1G------------------------------>-<------NLSKGERV----------------1236
CACNA1H------------------------------>-<------EDSCCLRL----------------1254
CACNA1I------------------------------>-<------DYTLCFRV----------------1130
CACNA1S------------------------------>-<------EIPLSPRP----------------758
cons                              > <                              

See full Alignment of Paralogues


Known Variants in SCN5A

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.A1088Tc.3262G>A Putative Benignrs369704754SIFT: tolerated
Polyphen: benign
p.A1088Vc.3263C>T Putative BenignSIFT:
Polyphen: