No paralogue variants have been mapped to residue 1245 for SCN5A.
| SCN5A | ILLSSGALAFEDIYLEERKTIKVLLEYADK>M<FTYVFVLEMLLKWVAYGF----KKYFTNAW | 1271 |
| SCN1A | ILLSSGALAFEDIYIDQRKTIKTMLEYADK>V<FTYIFILEMLLKWVAYGY----QTYFTNAW | 1284 |
| SCN2A | ILLSSGALAFEDIYIEQRKTIKTMLEYADK>V<FTYIFILEMLLKWVAYGF----QVYFTNAW | 1274 |
| SCN3A | ILLSSGALAFEDIYIEQRKTIKTMLEYADK>V<FTYIFILEMLLKWVAYGF----QTYFTNAW | 1272 |
| SCN4A | ILLSSGALAFEDIYIEQRRVIRTILEYADK>V<FTYIFIMEMLLKWVAYGF----KVYFTNAW | 1097 |
| SCN7A | TLLSTGTLAFEDIYMDQRKTIKILLEYADM>I<FTYIFILEMLLKWMAYGF----KAYFSNGW | 1000 |
| SCN8A | ILLSSGALAFEDIYIEQRKTIRTILEYADK>V<FTYIFILEMLLKWTAYGF----VKFFTNAW | 1264 |
| SCN9A | ILLSSGALAFEDIYIERKKTIKIILEYADK>I<FTYIFILEMLLKWIAYGY----KTYFTNAW | 1247 |
| SCN10A | ILLSSGSLAFEDYYLDQKPTVKALLEYTDR>V<FTFIFVFEMLLKWVAYGF----KKYFTNAW | 1218 |
| SCN11A | ILLSSGALIFEDVHLENQPKIQELLNCTDI>I<FTHIFILEMVLKWVAFGF----GKYFTSAW | 1122 |
| CACNA1A | IAMSSIALAAEDPV-QPNAPRNNVLRYFDY>V<FTGVFTFEMVIKMIDLGLVLHQGAYFRDLW | 1313 |
| CACNA1B | IALSSIALAAEDPV-RTDSPRNNALKYLDY>I<FTGVFTFEMVIKMIDLGLLLHPGAYFRDLW | 1220 |
| CACNA1C | ILLSSISLAAEDPV-QHTSFRNHILFYFDI>V<FTTIFTIEIALKMTAYGAFLHKGSFCRNYF | 969 |
| CACNA1D | IMLSSAALAAEDPI-RSHSFRNTILGYFDY>A<FTAIFTVEILLKMTTFGAFLHKGAFCRNYF | 975 |
| CACNA1E | IAASSIALAAEDPV-LTNSERNKVLRYFDY>V<FTGVFTFEMVIKMIDQGLILQDGSYFRDLW | 1222 |
| CACNA1F | IILSSVSLAAEDPI-RAHSFRNHILGYFDY>A<FTSIFTVEILLKMTVFGAFLHRGSFCRSWF | 940 |
| CACNA1G | IFLNCITIAMERPKIDPHSAERIFLTLSNY>I<FTAVFLAEMTVKVVALGWCFGEQAYLRSSW | 1346 |
| CACNA1H | IFLNCVTIALERPDIDPGSTERVFLSVSNY>I<FTAIFVAEMMVKVVALGLLSGEHAYLQSSW | 1364 |
| CACNA1I | IFLNCITIALERPQIEAGSTERIFLTVSNY>I<FTAIFVGEMTLKVVSLGLYFGEQAYLRSSW | 1240 |
| CACNA1S | ILLSSAALAAEDPI-RADSMRNQILKHFDI>G<FTSVFTVEIVLKMTTYGAFLHKGSFCRNYF | 868 |
| cons | > < |
| Protein | CDS | Disease Classification | Disease | dbSNP links | Effect Prediction |
|---|---|---|---|---|---|
| p.M1245I | c.3735G>A | Putative Benign | SIFT: Polyphen: |