The table below lists the 0 rare (MAF<0.0001 in ExAC) truncating TPM1 variants identified in a cohort of 4447 HCM patients (1535 patients from OMGL, 2912 patients from LMM). As the background population rate of rare truncating TPM1 variants (0.00004) is greater than this case frequency (0.00000), there is no excess of variants in this HCM patient cohort, suggesting that truncating TPM1 variants are not causative for HCM.
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