FHOD3 missense variants in ExAC

FHOD3 gene summary
FHOD3 variants in

The table below lists the FHOD3 missense variants found in the ExAC population database. Click on each variant for more details, including presence in the 1000 Genomes and Exome Sequencing Project databases, a breakdown by ethnic class and the variant's role in inherited cardiac disease. Use the form below to customise the variant selection. The table can be sorted by variant location, variant type or ExAC frequency.




No. Genomic coord.✝ Variant (CDS)▼ Variant (Protein) Variant Type▼ ExAC frequency▼Populations*
1. 34324091 c.3451G>A p.V1151I missense 0.34153078●●●●●●
2. 34273279 c.1604C>G p.A535G missense 0.13577449●●●●●●
3. 34156497 c.595A>G p.I199V missense 0.03253300●●●●●●
4. 34289142 c.1796A>G p.Q599R missense 0.02868527●●●●●●
5. 34289285 c.1939G>T p.V647F missense 0.01353728●●●●●●
6. 34261511 c.1423C>T p.R475W missense 0.01020746●●●●●●
7. 34349252 c.4100G>C p.G1367A missense 0.00465017●●●●●●
8. 34273314 c.1639C>T p.P547S missense 0.00356917●●●●●●
9. 34349354 c.4202G>A p.R1401K missense 0.00264223●●●●●●
10. 34298542 c.2756G>A p.R919Q missense 0.00250672●●●●●●
11. 34261473 c.1385G>A p.R462Q missense 0.00150150●●●●●●
12. 34289081 c.1735G>A p.E579K missense 0.00128490●●●●●●
13. 34238055 c.1214A>G p.N405S missense 0.00105466●●●●●●
14. 34349311 c.4159G>A p.V1387I missense 0.00093917●●●●●●
15. 34298406 c.2620G>A p.V874I missense 0.00093439●●●●●●
16. 34174816 c.673G>A p.A225T missense 0.00073389●●●●●●
17. 34205520 c.1004C>G p.P335R missense 0.00060770●●●●●●
18. 34261475 c.1387C>T p.R463W missense 0.00056128●●●●●●
19. 34156465 c.563G>A p.R188H missense 0.00055216●●●●●●
20. 34320704 c.3137G>A p.S1046N missense 0.00043693●●●●●●
21. 34238099 c.1258C>T p.P420S missense 0.00043685●●●●●●
22. 34340640 c.3970G>A p.A1324T missense 0.00039957●●●●●●
23. 34205580 c.1064G>A p.R355Q missense 0.00033416●●●●●●
24. 33877878 c.80G>C p.R27P missense 0.00033144●●●●●●
25. 34238130 c.1289C>G p.P430R missense 0.00032966●●●●●●
26. 34298059 c.2273A>G p.N758S missense 0.00029541●●●●●●
27. 34205532 c.1016G>A p.R339Q missense 0.00022460●●●●●●
28. 34205655 c.1139C>T p.P380L missense 0.00022299●●●●●●
29. 34267092 c.1447C>G p.R483G missense 0.00019668●●●●●●
30. 34182694 c.776C>T p.T259M missense 0.00016473●●●●●●
31. 33935574 c.238C>T p.R80W missense 0.00014844●●●●●●
32. 34340604 c.3934C>G p.P1312A missense 0.00013815●●●●●●
33. 34205582 c.1066G>A p.G356S missense 0.00012513●●●●●●
34. 33935575 c.239G>A p.R80Q missense 0.00012371●●●●●●
35. 34156464 c.562C>T p.R188C missense 0.00012363●●●●●●
36. 34273313 c.1638C>G p.S546R missense 0.00011675●●●●●●
37. 34273345 c.1670C>T p.T557M missense 0.00010987●●●●●●
38. 34289205 c.1859C>T p.P620L missense 0.00010738●●●●●●
39. 34205525 c.1009G>A p.G337R missense 0.00009943●●●●●●
40. 34298521 c.2735G>A p.R912H missense 0.00009903●●●●●●
41. 34298575 c.2789G>A p.R930H missense 0.00009890●●●●●●
42. 34298074 c.2288A>G p.K763R missense 0.00009548●●●●●●
43. 34273240 c.1565G>A p.R522Q missense 0.00009500●●●●●●
44. 34205474 c.958G>T p.V320L missense 0.00009239●●●●●●
45. 34298374 c.2588C>T p.P863L missense 0.00009088●●●●●●
46. 34349270 c.4118A>G p.N1373S missense 0.00009064●●●●●●
47. 34238070 c.1229C>A p.S410Y missense 0.00009063●●●●●●
48. 34205537 c.1021C>G p.R341G missense 0.00008933●●●●●●
49. 34273228 c.1553G>A p.R518Q missense 0.00008706●●●●●●
50. 34174789 c.646G>A p.V216I missense 0.00008427●●●●●●
51. 34298143 c.2357A>G p.N786S missense 0.00008415●●●●●●
52. 34298176 c.2390C>T p.P797L missense 0.00008262●●●●●●
53. 34310709 c.2993C>T p.T998M missense 0.00008237●●●●●●
54. 34298140 c.2354C>T p.P785L missense 0.00007595●●●●●●
55. 34298164 c.2378C>T p.A793V missense 0.00007486●●●●●●
56. 34205683 c.1167G>T p.K389N missense 0.00007464●●●●●●
57. 34205640 c.1124C>T p.S375L missense 0.00007435●●●●●●
58. 34298574 c.2788C>T p.R930C missense 0.00007418●●●●●●
59. 34205526 c.1010G>A p.G337E missense 0.00007228●●●●●●
60. 34174753 c.610C>T p.R204C missense 0.00006982●●●●●●
61. 34081919 c.362G>A p.R121Q missense 0.00006748●●●●●●
62. 34298257 c.2471A>G p.D824G missense 0.00006643●●●●●●
63. 34324023 c.3383A>C p.E1128A missense 0.00006631●●●●●●
64. 34310762 c.3046A>G p.I1016V missense 0.00006598●●●●●●
65. 33935533 c.197A>G p.N66S missense 0.00006595●●●●●●
66. 34273227 c.1552C>T p.R518W missense 0.00006105●●●●●●
67. 34297906 c.2120C>T p.P707L missense 0.00005788●●●●●●
68. 34320629 c.3062C>T p.T1021M missense 0.00005775●●●●●●
69. 34261476 c.1388G>A p.R463Q missense 0.00005775●●●●●●
70. 34205537 c.1021C>T p.R341W missense 0.00005360●●●●●●
71. 34205538 c.1022G>A p.R341Q missense 0.00005336●●●●●●
72. 33952644 c.274C>T p.R92W missense 0.00005114●●●●●●
73. 34273273 c.1598C>T p.S533L missense 0.00005073●●●●●●
74. 34289097 c.1751C>T p.P584L missense 0.00004995●●●●●●
75. 34205592 c.1076G>A p.R359H missense 0.00004988●●●●●●
76. 33935607 c.271G>A p.G91R missense 0.00004987●●●●●●
77. 34261506 c.1418T>C p.I473T missense 0.00004962●●●●●●
78. 34092458 c.463A>G p.K155E missense 0.00004959●●●●●●
79. 34322791 c.3326C>A p.A1109D missense 0.00004954●●●●●●
80. 34238123 c.1282T>C p.S428P missense 0.00004943●●●●●●
81. 33877845 c.47C>T p.P16L missense 0.00004831●●●●●●
82. 33877851 c.53A>G p.N18S missense 0.00004778●●●●●●
83. 34340686 c.4016C>G p.P1339R missense 0.00004296●●●●●●
84. 34297845 c.2059G>A p.D687N missense 0.00004290●●●●●●
85. 33877893 c.95C>A p.T32K missense 0.00004255●●●●●●
86. 34340668 c.3998T>C p.V1333A missense 0.00004255●●●●●●
87. 34289060 c.1714A>T p.S572C missense 0.00004210●●●●●●
88. 33877907 c.109C>G p.L37V missense 0.00004186●●●●●●
89. 34326930 c.3539A>T p.D1180V missense 0.00004162●●●●●●
90. 34205591 c.1075C>T p.R359C missense 0.00004158●●●●●●
91. 34349366 c.4214G>A p.R1405Q missense 0.00004151●●●●●●
92. 34261521 c.1433G>T p.R478I missense 0.00004149●●●●●●
93. 34205604 c.1088G>A p.R363H missense 0.00004145●●●●●●
94. 34205613 c.1097C>T p.S366L missense 0.00004139●●●●●●
95. 34298448 c.2662G>A p.A888T missense 0.00004135●●●●●●
96. 34359431 c.4258G>A p.G1420S missense 0.00004134●●●●●●
97. 34320769 c.3202G>A p.A1068T missense 0.00004124●●●●●●
98. 34327022 c.3631C>T p.R1211W missense 0.00004122●●●●●●
99. 34324127 c.3487G>C p.E1163Q missense 0.00004122●●●●●●
100. 34298572 c.2786G>A p.R929Q missense 0.00004121●●●●●●
101. 34238121 c.1280T>A p.V427D missense 0.00004120●●●●●●
102. 34310669 c.2953G>A p.A985T missense 0.00004118●●●●●●
103. 34340699 c.4029C>A p.D1343E missense 0.00003497●●●●●●
104. 34298043 c.2257G>A p.V753I missense 0.00003474●●●●●●
105. 34273233 c.1558G>A p.V520M missense 0.00003469●●●●●●
106. 34298085 c.2299G>C p.E767Q missense 0.00003465●●●●●●
107. 34205552 c.1036G>A p.V346M missense 0.00003449●●●●●●
108. 34320643 c.3076G>A p.D1026N missense 0.00003431●●●●●●
109. 34298121 c.2335A>G p.I779V missense 0.00003418●●●●●●
110. 34174814 c.671A>G p.N224S missense 0.00003407●●●●●●
111. 34298134 c.2348C>G p.A783G missense 0.00003391●●●●●●
112. 34273347 c.1672G>A p.V558M missense 0.00003384●●●●●●
113. 34297963 c.2177C>T p.A726V missense 0.00003377●●●●●●
114. 34297957 c.2171C>T p.A724V missense 0.00003360●●●●●●
115. 34298149 c.2363A>G p.K788R missense 0.00003355●●●●●●
116. 34205701 c.1185T>A p.D395E missense 0.00003352●●●●●●
117. 34298401 c.2615C>A p.P872H missense 0.00003352●●●●●●
118. 34192048 c.947A>G p.N316S missense 0.00003316●●●●●●
119. 34261512 c.1424G>A p.R475Q missense 0.00003312●●●●●●
120. 34298474 c.2688G>C p.Q896H missense 0.00003306●●●●●●
121. 34191951 c.850G>A p.D284N missense 0.00003305●●●●●●
122. 34156414 c.512C>G p.A171G missense 0.00003305●●●●●●
123. 34320679 c.3112G>A p.A1038T missense 0.00003303●●●●●●
124. 34192029 c.928G>A p.D310N missense 0.00003302●●●●●●
125. 34238120 c.1279G>A p.V427I missense 0.00003296●●●●●●
126. 34182657 c.739A>G p.I247V missense 0.00003295●●●●●●
127. 34182645 c.727C>A p.P243T missense 0.00003295●●●●●●
128. 34205478 c.962C>T p.A321V missense 0.00002771●●●●●●
129. 34205508 c.992C>T p.T331M missense 0.00002744●●●●●●
130. 34205520 c.1004C>A p.P335H missense 0.00002721●●●●●●
131. 34205531 c.1015C>T p.R339W missense 0.00002703●●●●●●
132. 34297802 c.2016G>C p.W672C missense 0.00002688●●●●●●
133. 34273208 c.1533C>G p.H511Q missense 0.00002675●●●●●●
134. 34335225 c.3851G>A p.R1284Q missense 0.00002648●●●●●●
135. 34273372 c.1697C>T p.P566L missense 0.00002648●●●●●●
136. 34298061 c.2275C>G p.R759G missense 0.00002610●●●●●●
137. 34273239 c.1564C>T p.R522W missense 0.00002594●●●●●●
138. 34298101 c.2315G>A p.G772E missense 0.00002587●●●●●●
139. 34340608 c.3938G>T p.S1313I missense 0.00002583●●●●●●
140. 34340614 c.3944C>T p.P1315L missense 0.00002569●●●●●●
141. 33952645 c.275G>A p.R92Q missense 0.00002552●●●●●●
142. 34340641 c.3971C>T p.A1324V missense 0.00002550●●●●●●
143. 33952690 c.320G>A p.R107K missense 0.00002524●●●●●●
144. 34298151 c.2365G>T p.V789F missense 0.00002513●●●●●●
145. 34298277 c.2491A>C p.I831L missense 0.00002510●●●●●●
146. 34349372 c.4220G>A p.R1407Q missense 0.00002510●●●●●●
147. 34205697 c.1181G>A p.R394Q missense 0.00002508●●●●●●
148. 34289313 c.1967G>C p.R656T missense 0.00002505●●●●●●
149. 34335161 c.3787A>G p.I1263V missense 0.00002494●●●●●●
150. 34297878 c.2092A>T p.M698L missense 0.00002490●●●●●●
151. 34192045 c.944T>C p.L315P missense 0.00002486●●●●●●
152. 34289162 c.1816G>A p.E606K missense 0.00002480●●●●●●
153. 34205646 c.1130C>T p.P377L missense 0.00002478●●●●●●
154. 34298622 c.2836A>G p.T946A missense 0.00002477●●●●●●
155. 34261413 c.1325G>A p.G442D missense 0.00002474●●●●●●
156. 34349264 c.4112C>T p.S1371L missense 0.00002472●●●●●●
157. 34349300 c.4148T>C p.M1383T missense 0.00002471●●●●●●
158. 34182646 c.728C>A p.P243H missense 0.00002471●●●●●●
159. 34081936 c.379C>G p.L127V missense 0.00002214●●●●●●
160. 34267093 c.1448G>A p.R483Q missense 0.00001957●●●●●●
161. 34273197 c.1522G>T p.A508S missense 0.00001838●●●●●●
162. 34205511 c.995A>G p.E332G missense 0.00001825●●●●●●
163. 34298359 c.2573C>T p.P858L missense 0.00001814●●●●●●
164. 34174837 c.694G>A p.V232I missense 0.00001789●●●●●●
165. 34297806 c.2020G>A p.A674T missense 0.00001785●●●●●●
166. 34297810 c.2024G>A p.G675D missense 0.00001778●●●●●●
167. 34273209 c.1534G>A p.E512K missense 0.00001777●●●●●●
168. 34340586 c.3916G>A p.G1306S missense 0.00001763●●●●●●
169. 34298061 c.2275C>T p.R759W missense 0.00001740●●●●●●
170. 34298062 c.2276G>A p.R759Q missense 0.00001738●●●●●●
171. 34174757 c.614T>A p.L205Q missense 0.00001724●●●●●●
172. 34340685 c.4015C>T p.P1339S missense 0.00001718●●●●●●
173. 34298113 c.2327G>T p.R776I missense 0.00001716●●●●●●
174. 34340679 c.4009T>G p.S1337A missense 0.00001711●●●●●●
175. 34191916 c.815C>T p.T272M missense 0.00001705●●●●●●
176. 34340652 c.3982G>A p.E1328K missense 0.00001698●●●●●●
177. 34174772 c.629C>T p.A210V missense 0.00001696●●●●●●
178. 34205567 c.1051G>A p.G351R missense 0.00001689●●●●●●
179. 34326918 c.3527A>C p.D1176A missense 0.00001686●●●●●●
180. 33952684 c.314C>G p.S105C missense 0.00001681●●●●●●
181. 34205706 c.1190G>A p.R397H missense 0.00001681●●●●●●
182. 34205705 c.1189C>T p.R397C missense 0.00001681●●●●●●
183. 34289327 c.1981G>A p.D661N missense 0.00001678●●●●●●
184. 34298400 c.2614C>G p.P872A missense 0.00001678●●●●●●
185. 34297863 c.2077C>T p.R693W missense 0.00001677●●●●●●
186. 34335186 c.3812G>A p.R1271H missense 0.00001674●●●●●●
187. 34349371 c.4219C>G p.R1407G missense 0.00001673●●●●●●
188. 34289304 c.1958C>T p.T653M missense 0.00001666●●●●●●
189. 34326930 c.3539A>C p.D1180A missense 0.00001665●●●●●●
190. 34298263 c.2477G>C p.G826A missense 0.00001664●●●●●●
191. 34335168 c.3794A>T p.E1265V missense 0.00001664●●●●●●
192. 34335119 c.3745T>A p.Y1249N missense 0.00001663●●●●●●
193. 34349366 c.4214G>T p.R1405L missense 0.00001661●●●●●●
194. 34359477 c.4304C>T p.S1435L missense 0.00001660●●●●●●
195. 33935604 c.268G>A p.A90T missense 0.00001660●●●●●●
196. 34205603 c.1087C>T p.R363C missense 0.00001658●●●●●●
197. 34327056 c.3665G>T p.R1222L missense 0.00001658●●●●●●
198. 34298244 c.2458A>G p.M820V missense 0.00001656●●●●●●
199. 34297887 c.2101G>A p.A701T missense 0.00001656●●●●●●
200. 34261510 c.1422G>T p.E474D missense 0.00001655●●●●●●
201. 34297923 c.2137G>C p.G713R missense 0.00001655●●●●●●
202. 34298454 c.2668C>G p.Q890E missense 0.00001654●●●●●●
203. 34298455 c.2669A>G p.Q890R missense 0.00001654●●●●●●
204. 34298457 c.2671G>T p.G891C missense 0.00001654●●●●●●
205. 34298451 c.2665C>T p.P889S missense 0.00001654●●●●●●
206. 34205633 c.1117A>T p.T373S missense 0.00001653●●●●●●
207. 34289168 c.1822G>A p.A608T missense 0.00001653●●●●●●
208. 34298463 c.2677G>C p.G893R missense 0.00001653●●●●●●
209. 34205653 c.1137T>A p.S379R missense 0.00001652●●●●●●
210. 34191954 c.853G>A p.V285I missense 0.00001651●●●●●●
211. 34324056 c.3416A>G p.K1139R missense 0.00001651●●●●●●
212. 34298187 c.2401T>C p.S801P missense 0.00001650●●●●●●
213. 34349342 c.4190G>A p.R1397Q missense 0.00001650●●●●●●
214. 34298615 c.2829G>T p.K943N missense 0.00001650●●●●●●
215. 34298205 c.2419C>A p.Q807K missense 0.00001650●●●●●●
216. 34349351 c.4199C>T p.P1400L missense 0.00001650●●●●●●
217. 34261407 c.1319C>T p.P440L missense 0.00001650●●●●●●
218. 34092438 c.443A>G p.E148G missense 0.00001650●●●●●●
219. 34326955 c.3564A>T p.R1188S missense 0.00001650●●●●●●
220. 34261472 c.1384C>T p.R462W missense 0.00001650●●●●●●
221. 34327031 c.3640G>A p.E1214K missense 0.00001649●●●●●●
222. 34156492 c.590C>T p.T197I missense 0.00001649●●●●●●
223. 34324125 c.3485C>T p.S1162L missense 0.00001649●●●●●●
224. 34349338 c.4186C>A p.Q1396K missense 0.00001649●●●●●●
225. 34261413 c.1325G>C p.G442A missense 0.00001649●●●●●●
226. 34320694 c.3127C>G p.P1043A missense 0.00001649●●●●●●
227. 34349339 c.4187A>G p.Q1396R missense 0.00001649●●●●●●
228. 34324133 c.3493G>A p.G1165R missense 0.00001649●●●●●●
229. 34322749 c.3284A>G p.E1095G missense 0.00001648●●●●●●
230. 34349306 c.4154G>A p.R1385H missense 0.00001648●●●●●●
231. 34156455 c.553G>A p.V185I missense 0.00001648●●●●●●
232. 34326990 c.3599C>G p.A1200G missense 0.00001648●●●●●●
233. 34349308 c.4156A>G p.I1386V missense 0.00001648●●●●●●
234. 34191990 c.889G>A p.V297M missense 0.00001648●●●●●●
235. 34349312 c.4160T>C p.V1387A missense 0.00001648●●●●●●
236. 34182721 c.803T>C p.L268S missense 0.00001647●●●●●●
237. 34298364 c.2578C>T p.P860S missense 0.00001379●●●●●●
238. 34335267 c.3893T>C p.I1298T missense 0.00001204●●●●●●
239. 34081910 c.353C>G p.S118C missense 0.00001191●●●●●●
240. 34081915 c.358G>A p.G120R missense 0.00001148●●●●●●
241. 34298337 c.2551C>G p.P851A missense 0.00001112●●●●●●
242. 34081922 c.365A>G p.D122G missense 0.00001111●●●●●●
243. 34298331 c.2545C>T p.P849S missense 0.00001100●●●●●●
244. 34081928 c.371G>T p.R124I missense 0.00001098●●●●●●
245. 34267128 c.1483G>A p.A495T missense 0.00000991●●●●●●
246. 34174856 c.713A>G p.K238R missense 0.00000986●●●●●●
247. 34340737 c.4067C>G p.A1356G missense 0.00000976●●●●●●
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497. 34349252 c.4100G>A p.G1367E missense 0.00000824●●●●●●
498. 33935548 c.212A>C p.D71A missense 0.00000824●●●●●●
499. 34238133 c.1292A>G p.Q431R missense 0.00000824●●●●●●
500. 34310676 c.2960A>G p.N987S missense 0.00000824●●●●●●
501. 34156477 c.575T>G p.I192S missense 0.00000824●●●●●●
502. 34156464 c.562C>A p.R188S missense 0.00000824●●●●●●
503. 34349305 c.4153C>T p.R1385C missense 0.00000824●●●●●●
504. 34298595 c.2809T>A p.S937T missense 0.00000824●●●●●●
505. 34322767 c.3302G>A p.G1101D missense 0.00000824●●●●●●

* This highlights the relative frequency of the variant in the ExAC populations - Non-Finnish European, African, East Asian, South Asian, American and Finnish. Higher frequencies are denoted by darker shades of green, variants absent in a population are coloured light gray.

✝ Genomic coordinates refer to the GRCh37 release of the human genome.