IL10 variants in ExAC

IL10 gene summary
IL10 variants in

The table below lists the IL10 variants found in the ExAC population database. Click on each variant for more details, including presence in the 1000 Genomes and Exome Sequencing Project databases, a breakdown by ethnic class and the variant's role in inherited cardiac disease. Use the form below to customise the variant selection. The table can be sorted by variant location, variant type or ExAC frequency.




No. Genomic coord.✝ Variant (CDS)▼ Variant (Protein) Variant Type▼ ExAC frequency▼Populations*
1. 206945738 c.43G>A p.G15R missense 0.00188757●●●●●●
2. 206945608 c.165+8T>C splice site 0.00054403●●●●●●
3. 206945725 c.56G>A p.S19N missense 0.00015658●●●●●●
4. 206943235 c.383G>T p.R128L missense 0.00014858●●●●●●
5. 206945723 c.58C>T p.P20S missense 0.00012362●●●●●●
6. 206941988 c.530G>A p.R177Q missense 0.00008540●●●●●●
7. 206944259 c.371G>A p.R124Q missense 0.00008236●●●●●●
8. 206945744 c.37C>A p.L13M missense 0.00004121●●●●●●
9. 206945663 c.118A>G p.M40V missense 0.00004119●●●●●●
10. 206944316 c.314T>G p.I105S missense 0.00004118●●●●●●
11. 206941984 c.534C>A p.N178K missense 0.00003433●●●●●●
12. 206944402 c.228T>C p.G76G splice site 0.00003295●●●●●●
13. 206942066 c.452A>C p.E151A missense 0.00002547●●●●●●
14. 206944695 c.225+6A>G splice site 0.00002499●●●●●●
15. 206945647 c.134G>A p.R45Q missense 0.00002472●●●●●●
16. 206944287 c.343A>T p.N115Y missense 0.00002471●●●●●●
17. 206944715 c.211C>A p.L71M missense 0.00001745●●●●●●
18. 206941989 c.529C>T p.R177X nonsense 0.00001705●●●●●●
19. 206942066 c.452A>G p.E151G missense 0.00001698●●●●●●
20. 206941997 c.521T>C p.M174T missense 0.00001692●●●●●●
21. 206942004 c.514A>G p.M172V missense 0.00001683●●●●●●
22. 206942011 c.507A>C p.E169D missense 0.00001677●●●●●●
23. 206943236 c.382C>T p.R128X nonsense 0.00001652●●●●●●
24. 206945762 c.19C>T p.L7F missense 0.00001650●●●●●●
25. 206945702 c.79G>A p.E27K missense 0.00001648●●●●●●
26. 206945612 c.165+4A>C splice site 0.00001648●●●●●●
27. 206945620 c.161T>C p.F54S missense 0.00001648●●●●●●
28. 206944381 c.249G>T p.L83F missense 0.00001647●●●●●●
29. 206944265 c.365G>A p.R122K missense 0.00001647●●●●●●
30. 206944256 c.374G>A p.R125H missense 0.00001647●●●●●●
31. 206944345 c.285G>A p.M95I missense 0.00001647●●●●●●
32. 206944409 c.226-5C>G splice site 0.00001647●●●●●●
33. 206944765 c.166-5T>G splice site 0.00001419●●●●●●
34. 206944761 c.166-1G>A essential splice site 0.00001338●●●●●●
35. 206944738 c.188A>G p.N63S missense 0.00001048●●●●●●
36. 206944723 c.203A>G p.E68G missense 0.00000913●●●●●●
37. 206942073 c.445C>T p.L149F missense 0.00000859●●●●●●
38. 206941995 c.523A>G p.K175E missense 0.00000847●●●●●●
39. 206942025 c.493A>G p.I165V missense 0.00000836●●●●●●
40. 206945762 c.19C>G p.L7V missense 0.00000825●●●●●●
41. 206945673 c.108C>A p.N36K missense 0.00000824●●●●●●
42. 206945656 c.125G>A p.R42Q missense 0.00000824●●●●●●
43. 206944271 c.359G>A p.R120K missense 0.00000824●●●●●●
44. 206945750 c.31G>A p.V11I missense 0.00000824●●●●●●
45. 206945637 c.144C>A p.F48L missense 0.00000824●●●●●●
46. 206944353 c.277G>C p.E93Q missense 0.00000824●●●●●●
47. 206944328 c.302A>G p.Q101R missense 0.00000824●●●●●●
48. 206943184 c.434C>T p.A145V missense 0.00000824●●●●●●
49. 206945689 c.92C>T p.T31I missense 0.00000824●●●●●●
50. 206945660 c.121C>T p.L41F missense 0.00000824●●●●●●
51. 206944386 c.244G>T p.A82S missense 0.00000824●●●●●●
52. 206945618 c.163T>C p.F55L missense 0.00000824●●●●●●
53. 206944289 c.341A>G p.E114G missense 0.00000824●●●●●●
54. 206945644 c.137A>G p.D46G missense 0.00000824●●●●●●
55. 206944356 c.274G>A p.E92K missense 0.00000824●●●●●●
56. 206944257 c.373C>A p.R125S missense 0.00000824●●●●●●
57. 206943184 c.434C>A p.A145D missense 0.00000824●●●●●●
58. 206944411 c.226-7C>A splice site 0.00000824●●●●●●
59. 206945620 c.161T>A p.F54Y missense 0.00000824●●●●●●
60. 206944310 c.320C>T p.A107V missense 0.00000824●●●●●●
61. 206944329 c.301C>A p.Q101K missense 0.00000824●●●●●●
62. 206943168 c.444+6C>T splice site 0.00000824●●●●●●
63. 206945648 c.133C>T p.R45X nonsense 0.00000824●●●●●●
64. 206944359 c.271C>G p.L91V missense 0.00000824●●●●●●
65. 206944260 c.370C>T p.R124W missense 0.00000824●●●●●●
66. 206945687 c.94C>T p.H32Y missense 0.00000824●●●●●●
67. 206944323 c.307C>T p.P103S missense 0.00000824●●●●●●
68. 206944341 c.289delC p.Gln97LysfsTer13 frameshift 0.00000824●●●●●●

* This highlights the relative frequency of the variant in the ExAC populations - Non-Finnish European, African, East Asian, South Asian, American and Finnish. Higher frequencies are denoted by darker shades of green, variants absent in a population are coloured light gray.

✝ Genomic coordinates refer to the GRCh37 release of the human genome.