KLF10 missense variants in ExAC

KLF10 gene summary
KLF10 variants in

The table below lists the KLF10 missense variants found in the ExAC population database. Click on each variant for more details, including presence in the 1000 Genomes and Exome Sequencing Project databases, a breakdown by ethnic class and the variant's role in inherited cardiac disease. Use the form below to customise the variant selection. The table can be sorted by variant location, variant type or ExAC frequency.




No. Genomic coord.✝ Variant (CDS)▼ Variant (Protein) Variant Type▼ ExAC frequency▼Populations*
1. 103663814 c.746C>T p.S249F missense 0.01345894●●●●●●
2. 103663994 c.566C>G p.T189S missense 0.00221560●●●●●●
3. 103664003 c.557G>T p.R186I missense 0.00221560●●●●●●
4. 103667800 c.30G>C p.Q10H missense 0.00118127●●●●●●
5. 103663614 c.946G>A p.A316T missense 0.00080044●●●●●●
6. 103663886 c.674G>A p.S225N missense 0.00060953●●●●●●
7. 103663473 c.1087T>G p.S363A missense 0.00022071●●●●●●
8. 103664226 c.334C>T p.P112S missense 0.00021916●●●●●●
9. 103663999 c.561A>T p.R187S missense 0.00015649●●●●●●
10. 103664484 c.178G>T p.V60F missense 0.00014830●●●●●●
11. 103663755 c.805C>T p.P269S missense 0.00014043●●●●●●
12. 103663953 c.607G>T p.A203S missense 0.00009060●●●●●●
13. 103664582 c.80T>C p.M27T missense 0.00008244●●●●●●
14. 103663497 c.1063G>T p.A355S missense 0.00007829●●●●●●
15. 103664166 c.394G>A p.A132T missense 0.00007542●●●●●●
16. 103664124 c.436A>G p.K146E missense 0.00007488●●●●●●
17. 103663517 c.1043C>T p.P348L missense 0.00006066●●●●●●
18. 103663391 c.1169C>T p.T390M missense 0.00005425●●●●●●
19. 103663619 c.941A>G p.K314R missense 0.00005143●●●●●●
20. 103664174 c.386A>T p.H129L missense 0.00005031●●●●●●
21. 103664488 c.174A>C p.K58N missense 0.00004943●●●●●●
22. 103663914 c.646A>G p.T216A missense 0.00004942●●●●●●
23. 103663911 c.649G>A p.V217M missense 0.00004942●●●●●●
24. 103664223 c.337G>C p.A113P missense 0.00004214●●●●●●
25. 103663863 c.697G>A p.V233M missense 0.00004119●●●●●●
26. 103663992 c.568C>A p.H190N missense 0.00004118●●●●●●
27. 103663565 c.995C>T p.P332L missense 0.00003473●●●●●●
28. 103663649 c.911C>A p.P304H missense 0.00003361●●●●●●
29. 103664144 c.416A>G p.K139R missense 0.00003344●●●●●●
30. 103663692 c.868G>A p.V290I missense 0.00003319●●●●●●
31. 103662391 c.1412C>T p.A471V missense 0.00003297●●●●●●
32. 103663904 c.656A>T p.D219V missense 0.00003295●●●●●●
33. 103663587 c.973G>A p.V325I missense 0.00002602●●●●●●
34. 103663680 c.880C>T p.P294S missense 0.00002492●●●●●●
35. 103664426 c.236C>T p.P79L missense 0.00002477●●●●●●
36. 103664525 c.137T>C p.M46T missense 0.00002471●●●●●●
37. 103663901 c.659T>C p.V220A missense 0.00002471●●●●●●
38. 103663950 c.610G>A p.A204T missense 0.00002471●●●●●●
39. 103663566 c.994C>G p.P332A missense 0.00001736●●●●●●
40. 103664249 c.311C>T p.S104F missense 0.00001694●●●●●●
41. 103664231 c.329T>A p.M110K missense 0.00001688●●●●●●
42. 103664183 c.377C>G p.A126G missense 0.00001678●●●●●●
43. 103664168 c.392C>A p.A131D missense 0.00001677●●●●●●
44. 103664151 c.409G>A p.E137K missense 0.00001674●●●●●●
45. 103664140 c.420C>A p.S140R missense 0.00001671●●●●●●
46. 103664609 c.53T>C p.M18T missense 0.00001661●●●●●●
47. 103663682 c.878C>T p.T293I missense 0.00001661●●●●●●
48. 103663686 c.874A>G p.S292G missense 0.00001661●●●●●●
49. 103663701 c.859A>T p.T287S missense 0.00001658●●●●●●
50. 103664105 c.455C>T p.A152V missense 0.00001657●●●●●●
51. 103663707 c.853G>A p.V285I missense 0.00001657●●●●●●
52. 103664456 c.206C>G p.S69C missense 0.00001648●●●●●●
53. 103663823 c.737C>T p.A246V missense 0.00001648●●●●●●
54. 103664039 c.521C>T p.A174V missense 0.00001648●●●●●●
55. 103664054 c.506C>G p.T169S missense 0.00001648●●●●●●
56. 103663968 c.592A>G p.K198E missense 0.00001647●●●●●●
57. 103663925 c.635G>A p.C212Y missense 0.00001647●●●●●●
58. 103663899 c.661G>T p.D221Y missense 0.00001647●●●●●●
59. 103663400 c.1160A>C p.K387T missense 0.00000904●●●●●●
60. 103663431 c.1129G>A p.G377S missense 0.00000901●●●●●●
61. 103663439 c.1121C>T p.P374L missense 0.00000899●●●●●●
62. 103663440 c.1120C>T p.P374S missense 0.00000898●●●●●●
63. 103663457 c.1103G>A p.S368N missense 0.00000892●●●●●●
64. 103663470 c.1090T>A p.S364T missense 0.00000884●●●●●●
65. 103663484 c.1076C>A p.P359H missense 0.00000876●●●●●●
66. 103663553 c.1007C>T p.P336L missense 0.00000868●●●●●●
67. 103663556 c.1004G>T p.S335I missense 0.00000868●●●●●●
68. 103663572 c.988A>G p.K330E missense 0.00000868●●●●●●
69. 103663556 c.1004G>C p.S335T missense 0.00000868●●●●●●
70. 103663547 c.1013G>A p.G338D missense 0.00000868●●●●●●
71. 103663560 c.1000G>A p.V334M missense 0.00000868●●●●●●
72. 103663514 c.1046G>A p.G349E missense 0.00000867●●●●●●
73. 103663535 c.1025C>T p.S342F missense 0.00000866●●●●●●
74. 103664273 c.287A>G p.Y96C missense 0.00000854●●●●●●
75. 103663637 c.923T>G p.M308R missense 0.00000848●●●●●●
76. 103664253 c.307C>T p.P103S missense 0.00000848●●●●●●
77. 103664230 c.330G>A p.M110I missense 0.00000844●●●●●●
78. 103664228 c.332C>T p.A111V missense 0.00000843●●●●●●
79. 103664222 c.338C>T p.A113V missense 0.00000842●●●●●●
80. 103663646 c.914T>C p.V305A missense 0.00000842●●●●●●
81. 103664211 c.349G>A p.V117I missense 0.00000841●●●●●●
82. 103663650 c.910C>G p.P304A missense 0.00000840●●●●●●
83. 103664183 c.377C>T p.A126V missense 0.00000839●●●●●●
84. 103664181 c.379A>C p.K127Q missense 0.00000839●●●●●●
85. 103664177 c.383C>T p.P128L missense 0.00000838●●●●●●
86. 103664157 c.403A>G p.K135E missense 0.00000838●●●●●●
87. 103667817 c.13G>C p.G5R missense 0.00000837●●●●●●
88. 103667818 c.12C>A p.F4L missense 0.00000837●●●●●●
89. 103664400 c.262C>T p.P88S missense 0.00000836●●●●●●
90. 103663659 c.901G>A p.V301I missense 0.00000836●●●●●●
91. 103664136 c.424G>A p.V142I missense 0.00000835●●●●●●
92. 103667811 c.19T>G p.S7A missense 0.00000835●●●●●●
93. 103663664 c.896C>A p.P299Q missense 0.00000834●●●●●●
94. 103664129 c.431C>T p.A144V missense 0.00000833●●●●●●
95. 103667805 c.25C>A p.Q9K missense 0.00000833●●●●●●
96. 103667799 c.31A>C p.T11P missense 0.00000832●●●●●●
97. 103667801 c.29A>G p.Q10R missense 0.00000832●●●●●●
98. 103664611 c.51A>T p.E17D missense 0.00000832●●●●●●
99. 103663672 c.888C>A p.S296R missense 0.00000832●●●●●●
100. 103667795 c.35C>A p.A12E missense 0.00000831●●●●●●
101. 103664408 c.254A>C p.H85P missense 0.00000831●●●●●●
102. 103664608 c.54G>A p.M18I missense 0.00000830●●●●●●
103. 103663700 c.860C>G p.T287R missense 0.00000829●●●●●●
104. 103664109 c.451C>G p.Q151E missense 0.00000829●●●●●●
105. 103664412 c.250T>G p.F84V missense 0.00000829●●●●●●
106. 103663713 c.847A>C p.N283H missense 0.00000828●●●●●●
107. 103664604 c.58T>C p.S20P missense 0.00000828●●●●●●
108. 103664594 c.68C>T p.P23L missense 0.00000826●●●●●●
109. 103664073 c.487C>A p.Q163K missense 0.00000825●●●●●●
110. 103664075 c.485C>T p.A162V missense 0.00000825●●●●●●
111. 103664064 c.496A>G p.N166D missense 0.00000825●●●●●●
112. 103664559 c.103G>A p.E35K missense 0.00000824●●●●●●
113. 103662409 c.1394G>A p.S465N missense 0.00000824●●●●●●
114. 103664442 c.220G>A p.E74K missense 0.00000824●●●●●●
115. 103664003 c.557G>A p.R186K missense 0.00000824●●●●●●
116. 103662493 c.1310G>A p.R437Q missense 0.00000824●●●●●●
117. 103663940 c.620C>T p.P207L missense 0.00000824●●●●●●
118. 103663875 c.685T>C p.Y229H missense 0.00000824●●●●●●
119. 103664027 c.533T>C p.L178P missense 0.00000824●●●●●●
120. 103664054 c.506C>A p.T169N missense 0.00000824●●●●●●
121. 103663992 c.568C>T p.H190Y missense 0.00000824●●●●●●
122. 103662455 c.1348C>T p.R450C missense 0.00000824●●●●●●
123. 103663847 c.713C>T p.T238M missense 0.00000824●●●●●●
124. 103663818 c.742G>C p.V248L missense 0.00000824●●●●●●
125. 103664009 c.551C>A p.S184Y missense 0.00000824●●●●●●
126. 103664526 c.136A>G p.M46V missense 0.00000824●●●●●●
127. 103662391 c.1412C>G p.A471G missense 0.00000824●●●●●●
128. 103664469 c.193G>A p.V65I missense 0.00000824●●●●●●
129. 103664574 c.88T>C p.W30R missense 0.00000824●●●●●●
130. 103664061 c.499C>T p.H167Y missense 0.00000824●●●●●●
131. 103663958 c.602C>T p.P201L missense 0.00000824●●●●●●
132. 103662457 c.1346G>A p.R449Q missense 0.00000824●●●●●●
133. 103663994 c.566C>T p.T189I missense 0.00000824●●●●●●
134. 103662496 c.1307G>A p.R436Q missense 0.00000824●●●●●●
135. 103662504 c.1299G>A p.M433I missense 0.00000824●●●●●●
136. 103664015 c.545A>G p.N182S missense 0.00000824●●●●●●
137. 103664576 c.86C>A p.S29Y missense 0.00000824●●●●●●
138. 103664538 c.124G>A p.V42I missense 0.00000824●●●●●●
139. 103662404 c.1399C>A p.L467I missense 0.00000824●●●●●●
140. 103663870 c.690C>G p.D230E missense 0.00000824●●●●●●
141. 103664050 c.510C>G p.C170W missense 0.00000824●●●●●●
142. 103662568 c.1235G>A p.R412H missense 0.00000824●●●●●●
143. 103662458 c.1345C>G p.R449G missense 0.00000824●●●●●●
144. 103664506 c.156G>C p.W52C missense 0.00000824●●●●●●
145. 103663886 c.674G>C p.S225T missense 0.00000824●●●●●●
146. 103662389 c.1414C>A p.L472I missense 0.00000824●●●●●●
147. 103663826 c.734C>T p.P245L missense 0.00000824●●●●●●
148. 103664021 c.539A>C p.Y180S missense 0.00000824●●●●●●

* This highlights the relative frequency of the variant in the ExAC populations - Non-Finnish European, African, East Asian, South Asian, American and Finnish. Higher frequencies are denoted by darker shades of green, variants absent in a population are coloured light gray.

✝ Genomic coordinates refer to the GRCh37 release of the human genome.