NDRG4 missense variants in ExAC

NDRG4 gene summary
NDRG4 variants in

The table below lists the NDRG4 missense variants found in the ExAC population database. Click on each variant for more details, including presence in the 1000 Genomes and Exome Sequencing Project databases, a breakdown by ethnic class and the variant's role in inherited cardiac disease. Use the form below to customise the variant selection. The table can be sorted by variant location, variant type or ExAC frequency.




No. Genomic coord.✝ Variant (CDS)▼ Variant (Protein) Variant Type▼ ExAC frequency▼Populations*
1. 58537777 c.253A>G p.I85V missense 0.00130797●●●●●●
2. 58541762 c.827C>T p.T276M missense 0.00049677●●●●●●
3. 58541889 c.871G>A p.A291T missense 0.00030302●●●●●●
4. 58541740 c.805G>A p.G269R missense 0.00015768●●●●●●
5. 58538524 c.499G>A p.A167T missense 0.00015654●●●●●●
6. 58545452 c.1148T>C p.V383A missense 0.00013479●●●●●●
7. 58521705 c.83G>A p.R28Q missense 0.00013259●●●●●●
8. 58538309 c.451G>A p.V151M missense 0.00008271●●●●●●
9. 58541713 c.778C>T p.R260C missense 0.00007534●●●●●●
10. 58537747 c.223C>T p.R75W missense 0.00007447●●●●●●
11. 58540310 c.548T>C p.V183A missense 0.00007443●●●●●●
12. 58521723 c.101C>T p.P34L missense 0.00006765●●●●●●
13. 58521680 c.58A>G p.T20A missense 0.00006736●●●●●●
14. 58537727 c.203G>A p.G68D missense 0.00006625●●●●●●
15. 58537748 c.224G>A p.R75Q missense 0.00006620●●●●●●
16. 58540873 c.730G>A p.V244M missense 0.00005999●●●●●●
17. 58538324 c.466G>A p.G156R missense 0.00005793●●●●●●
18. 58540303 c.541G>A p.D181N missense 0.00005790●●●●●●
19. 58540486 c.640C>A p.P214T missense 0.00005529●●●●●●
20. 58541898 c.880G>A p.G294R missense 0.00005403●●●●●●
21. 58537807 c.283C>T p.H95Y missense 0.00004989●●●●●●
22. 58537768 c.244C>T p.R82C missense 0.00004965●●●●●●
23. 58541895 c.877G>A p.D293N missense 0.00004483●●●●●●
24. 58545373 c.1069C>T p.L357F missense 0.00004241●●●●●●
25. 58545379 c.1075A>G p.S359G missense 0.00004238●●●●●●
26. 58542894 c.914C>A p.T305N missense 0.00004210●●●●●●
27. 58541714 c.779G>A p.R260H missense 0.00004182●●●●●●
28. 58541767 c.832C>T p.R278C missense 0.00004138●●●●●●
29. 58540489 c.643G>A p.D215N missense 0.00004051●●●●●●
30. 58545347 c.1043G>A p.R348H missense 0.00003447●●●●●●
31. 58528877 c.142G>A p.D48N missense 0.00003408●●●●●●
32. 58538508 c.483T>G p.I161M missense 0.00003296●●●●●●
33. 58538100 c.326A>C p.Q109P missense 0.00003296●●●●●●
34. 58538507 c.482T>C p.I161T missense 0.00003296●●●●●●
35. 58538132 c.358G>A p.V120M missense 0.00003295●●●●●●
36. 58540506 c.660C>A p.H220Q missense 0.00002838●●●●●●
37. 58541859 c.841G>A p.V281M missense 0.00002574●●●●●●
38. 58540468 c.622G>A p.G208S missense 0.00002560●●●●●●
39. 58540856 c.713G>A p.R238Q missense 0.00002551●●●●●●
40. 58545389 c.1085C>T p.S362L missense 0.00002541●●●●●●
41. 58545403 c.1099C>T p.R367C missense 0.00002539●●●●●●
42. 58545398 c.1094G>T p.G365V missense 0.00002539●●●●●●
43. 58541718 c.783A>C p.R261S missense 0.00002503●●●●●●
44. 58541735 c.800G>A p.R267Q missense 0.00002493●●●●●●
45. 58537710 c.186C>G p.D62E missense 0.00002491●●●●●●
46. 58537769 c.245G>A p.R82H missense 0.00002483●●●●●●
47. 58537760 c.236A>G p.K79R missense 0.00002483●●●●●●
48. 58543212 c.977A>G p.K326R missense 0.00002475●●●●●●
49. 58538139 c.365C>T p.A122V missense 0.00002472●●●●●●
50. 58538536 c.511G>C p.V171L missense 0.00002472●●●●●●
51. 58540493 c.647C>T p.T216M missense 0.00002216●●●●●●
52. 58540886 c.743C>A p.A248D missense 0.00001762●●●●●●
53. 58528907 c.172T>G p.W58G missense 0.00001744●●●●●●
54. 58528884 c.149T>C p.F50S missense 0.00001710●●●●●●
55. 58540867 c.724G>A p.G242R missense 0.00001708●●●●●●
56. 58545460 c.1156A>G p.T386A missense 0.00001685●●●●●●
57. 58541734 c.799C>T p.R267W missense 0.00001662●●●●●●
58. 58537713 c.189C>G p.I63M missense 0.00001660●●●●●●
59. 58541744 c.809C>T p.T270M missense 0.00001659●●●●●●
60. 58538280 c.422T>C p.M141T missense 0.00001653●●●●●●
61. 58538072 c.298A>G p.N100D missense 0.00001649●●●●●●
62. 58538079 c.305T>G p.F102C missense 0.00001649●●●●●●
63. 58538097 c.323T>G p.M108R missense 0.00001648●●●●●●
64. 58538527 c.502G>A p.G168R missense 0.00001648●●●●●●
65. 58538163 c.389C>T p.S130L missense 0.00001648●●●●●●
66. 58538089 c.315C>G p.F105L missense 0.00001648●●●●●●
67. 58540477 c.631A>G p.S211G missense 0.00001437●●●●●●
68. 58540910 c.767T>C p.M256T missense 0.00000962●●●●●●
69. 58540891 c.748C>G p.L250V missense 0.00000892●●●●●●
70. 58541871 c.853G>A p.V285I missense 0.00000866●●●●●●
71. 58528898 c.163G>C p.D55H missense 0.00000865●●●●●●
72. 58528891 c.156G>C p.L52F missense 0.00000858●●●●●●
73. 58541854 c.836G>A p.C279Y missense 0.00000853●●●●●●
74. 58545358 c.1054T>C p.S352P missense 0.00000852●●●●●●
75. 58545361 c.1057C>G p.R353G missense 0.00000851●●●●●●
76. 58540837 c.694G>A p.E232K missense 0.00000851●●●●●●
77. 58542885 c.905T>A p.L302Q missense 0.00000849●●●●●●
78. 58545377 c.1073C>T p.T358I missense 0.00000848●●●●●●
79. 58545421 c.1117C>G p.H373D missense 0.00000845●●●●●●
80. 58545421 c.1117C>T p.H373Y missense 0.00000845●●●●●●
81. 58542891 c.911C>T p.P304L missense 0.00000844●●●●●●
82. 58545424 c.1120T>G p.S374A missense 0.00000844●●●●●●
83. 58545439 c.1135G>A p.G379R missense 0.00000842●●●●●●
84. 58545461 c.1157C>A p.T386N missense 0.00000842●●●●●●
85. 58545440 c.1136G>A p.G379E missense 0.00000842●●●●●●
86. 58545435 c.1131C>G p.S377R missense 0.00000842●●●●●●
87. 58545446 c.1142G>A p.G381D missense 0.00000842●●●●●●
88. 58541719 c.784G>T p.D262Y missense 0.00000834●●●●●●
89. 58541732 c.797A>T p.N266I missense 0.00000832●●●●●●
90. 58537804 c.280A>G p.N94D missense 0.00000831●●●●●●
91. 58537801 c.277C>T p.L93F missense 0.00000830●●●●●●
92. 58537714 c.190G>A p.E64K missense 0.00000830●●●●●●
93. 58537794 c.270T>A p.D90E missense 0.00000829●●●●●●
94. 58537723 c.199T>C p.Y67H missense 0.00000828●●●●●●
95. 58537760 c.236A>T p.K79M missense 0.00000828●●●●●●
96. 58537724 c.200A>T p.Y67F missense 0.00000828●●●●●●
97. 58537772 c.248C>T p.P83L missense 0.00000828●●●●●●
98. 58541768 c.833G>A p.R278H missense 0.00000828●●●●●●
99. 58537780 c.256C>G p.L86V missense 0.00000828●●●●●●
100. 58537730 c.206T>C p.L69P missense 0.00000828●●●●●●
101. 58538282 c.424G>A p.E142K missense 0.00000827●●●●●●
102. 58538315 c.457C>G p.Q153E missense 0.00000827●●●●●●
103. 58543247 c.1012A>C p.M338L missense 0.00000827●●●●●●
104. 58538283 c.425A>G p.E142G missense 0.00000827●●●●●●
105. 58543248 c.1013T>C p.M338T missense 0.00000827●●●●●●
106. 58540301 c.539C>A p.P180H missense 0.00000827●●●●●●
107. 58538294 c.436G>T p.A146S missense 0.00000827●●●●●●
108. 58537756 c.232C>T p.P78S missense 0.00000827●●●●●●
109. 58543223 c.988G>C p.A330P missense 0.00000825●●●●●●
110. 58538156 c.382G>C p.G128R missense 0.00000824●●●●●●
111. 58538093 c.319G>A p.D107N missense 0.00000824●●●●●●
112. 58538133 c.359T>G p.V120G missense 0.00000824●●●●●●
113. 58538516 c.491G>C p.G164A missense 0.00000824●●●●●●
114. 58538112 c.338A>G p.K113R missense 0.00000824●●●●●●
115. 58538499 c.474G>T p.K158N missense 0.00000824●●●●●●
116. 58538138 c.364G>A p.A122T missense 0.00000824●●●●●●
117. 58538521 c.496G>A p.G166S missense 0.00000824●●●●●●
118. 58538177 c.403G>A p.G135R missense 0.00000824●●●●●●
119. 58538160 c.386C>T p.A129V missense 0.00000824●●●●●●
120. 58543062 c.938C>T p.A313V missense 0.00000824●●●●●●
121. 58538071 c.297C>A p.F99L missense 0.00000824●●●●●●
122. 58538093 c.319G>C p.D107H missense 0.00000824●●●●●●
123. 58538178 c.404G>A p.G135E missense 0.00000824●●●●●●
124. 58538168 c.394T>C p.F132L missense 0.00000824●●●●●●

* This highlights the relative frequency of the variant in the ExAC populations - Non-Finnish European, African, East Asian, South Asian, American and Finnish. Higher frequencies are denoted by darker shades of green, variants absent in a population are coloured light gray.

✝ Genomic coordinates refer to the GRCh37 release of the human genome.