TRIM55 missense variants in ExAC

TRIM55 gene summary
TRIM55 variants in

The table below lists the TRIM55 missense variants found in the ExAC population database. Click on each variant for more details, including presence in the 1000 Genomes and Exome Sequencing Project databases, a breakdown by ethnic class and the variant's role in inherited cardiac disease. Use the form below to customise the variant selection. The table can be sorted by variant location, variant type or ExAC frequency.




No. Genomic coord.✝ Variant (CDS)▼ Variant (Protein) Variant Type▼ ExAC frequency▼Populations*
1. 67064654 c.1028A>G p.K343R missense 0.14103252●●●●●●
2. 67066396 c.1351C>T p.R451W missense 0.00191994●●●●●●
3. 67047301 c.418G>A p.E140K missense 0.00180381●●●●●●
4. 67047241 c.358G>T p.D120Y missense 0.00065108●●●●●●
5. 67066435 c.1390G>A p.E464K missense 0.00050261●●●●●●
6. 67066394 c.1349C>T p.T450I missense 0.00046968●●●●●●
7. 67061980 c.704G>A p.R235Q missense 0.00040366●●●●●●
8. 67086762 c.1581T>G p.S527R missense 0.00026585●●●●●●
9. 67066511 c.1466C>T p.A489V missense 0.00026424●●●●●●
10. 67061983 c.707C>T p.T236I missense 0.00025538●●●●●●
11. 67047352 c.469C>A p.Q157K missense 0.00024710●●●●●●
12. 67066367 c.1322T>G p.F441C missense 0.00019783●●●●●●
13. 67064719 c.1093G>A p.E365K missense 0.00019018●●●●●●
14. 67040600 c.230G>A p.R77H missense 0.00016485●●●●●●
15. 67040549 c.179C>T p.P60L missense 0.00014272●●●●●●
16. 67062681 c.965G>A p.R322H missense 0.00014008●●●●●●
17. 67047274 c.391C>T p.R131C missense 0.00014003●●●●●●
18. 67064800 c.1174C>A p.P392T missense 0.00013234●●●●●●
19. 67066544 c.1499C>T p.T500I missense 0.00011568●●●●●●
20. 67062012 c.736G>T p.A246S missense 0.00010709●●●●●●
21. 67061923 c.647A>G p.D216G missense 0.00009915●●●●●●
22. 67064788 c.1162C>G p.P388A missense 0.00007439●●●●●●
23. 67086718 c.1537G>T p.A513S missense 0.00007415●●●●●●
24. 67062015 c.739C>G p.L247V missense 0.00007414●●●●●●
25. 67047354 c.471G>C p.Q157H missense 0.00007413●●●●●●
26. 67064632 c.1006G>C p.E336Q missense 0.00006922●●●●●●
27. 67064686 c.1060G>A p.V354I missense 0.00005927●●●●●●
28. 67066516 c.1471G>A p.E491K missense 0.00005778●●●●●●
29. 67062624 c.908G>C p.G303A missense 0.00005767●●●●●●
30. 67040626 c.256G>A p.V86I missense 0.00005767●●●●●●
31. 67086721 c.1540C>T p.P514S missense 0.00005767●●●●●●
32. 67047376 c.493T>C p.F165L missense 0.00005766●●●●●●
33. 67064641 c.1015G>A p.G339R missense 0.00005607●●●●●●
34. 67062082 c.806T>G p.M269R missense 0.00004945●●●●●●
35. 67086731 c.1550A>G p.Q517R missense 0.00004944●●●●●●
36. 67062635 c.919A>G p.M307V missense 0.00004943●●●●●●
37. 67062692 c.976T>G p.F326V missense 0.00004121●●●●●●
38. 67086719 c.1538C>T p.A513V missense 0.00004120●●●●●●
39. 67062593 c.877A>G p.K293E missense 0.00004120●●●●●●
40. 67064644 c.1018G>A p.E340K missense 0.00003837●●●●●●
41. 67086793 c.1612T>G p.F538V missense 0.00003298●●●●●●
42. 67066355 c.1310C>T p.A437V missense 0.00003298●●●●●●
43. 67062637 c.921G>A p.M307I missense 0.00003296●●●●●●
44. 67047290 c.407G>C p.C136S missense 0.00003295●●●●●●
45. 67039576 c.73A>G p.I25V missense 0.00003295●●●●●●
46. 67062624 c.908G>A p.G303D missense 0.00003295●●●●●●
47. 67064678 c.1052G>T p.G351V missense 0.00002611●●●●●●
48. 67064825 c.1199C>T p.P400L missense 0.00002486●●●●●●
49. 67049376 c.554G>A p.R185Q missense 0.00002479●●●●●●
50. 67064752 c.1126G>T p.A376S missense 0.00002479●●●●●●
51. 67066518 c.1473G>T p.E491D missense 0.00002476●●●●●●
52. 67062582 c.866C>T p.S289L missense 0.00002474●●●●●●
53. 67062087 c.811G>A p.E271K missense 0.00002473●●●●●●
54. 67066401 c.1356A>T p.K452N missense 0.00002472●●●●●●
55. 67062596 c.880G>A p.A294T missense 0.00002472●●●●●●
56. 67062636 c.920T>G p.M307R missense 0.00002472●●●●●●
57. 67086752 c.1571C>T p.A524V missense 0.00002472●●●●●●
58. 67086717 c.1536G>C p.E512D missense 0.00002472●●●●●●
59. 67047371 c.488A>G p.H163R missense 0.00002471●●●●●●
60. 67062009 c.733C>T p.R245C missense 0.00002471●●●●●●
61. 67039604 c.101C>T p.T34M missense 0.00002471●●●●●●
62. 67064666 c.1040G>A p.G347E missense 0.00001861●●●●●●
63. 67064851 c.1225C>T p.P409S missense 0.00001668●●●●●●
64. 67066561 c.1516A>G p.T506A missense 0.00001660●●●●●●
65. 67061906 c.630G>C p.E210D missense 0.00001660●●●●●●
66. 67049346 c.524G>C p.G175A missense 0.00001657●●●●●●
67. 67066306 c.1261G>A p.E421K missense 0.00001654●●●●●●
68. 67066307 c.1262A>G p.E421G missense 0.00001654●●●●●●
69. 67064798 c.1172T>A p.L391H missense 0.00001654●●●●●●
70. 67049360 c.538G>A p.V180M missense 0.00001653●●●●●●
71. 67049363 c.541G>T p.G181C missense 0.00001652●●●●●●
72. 67049371 c.549C>A p.N183K missense 0.00001652●●●●●●
73. 67040582 c.212C>G p.A71G missense 0.00001652●●●●●●
74. 67066507 c.1462G>A p.A488T missense 0.00001652●●●●●●
75. 67066508 c.1463C>T p.A488V missense 0.00001651●●●●●●
76. 67066331 c.1286C>T p.P429L missense 0.00001651●●●●●●
77. 67086790 c.1609A>G p.I537V missense 0.00001649●●●●●●
78. 67040594 c.224G>A p.R75Q missense 0.00001649●●●●●●
79. 67061950 c.674G>A p.R225K missense 0.00001649●●●●●●
80. 67062689 c.973G>A p.D325N missense 0.00001648●●●●●●
81. 67062603 c.887A>T p.Q296L missense 0.00001648●●●●●●
82. 67040608 c.238T>C p.S80P missense 0.00001648●●●●●●
83. 67086739 c.1558G>T p.A520S missense 0.00001648●●●●●●
84. 67047251 c.368T>C p.M123T missense 0.00001648●●●●●●
85. 67086749 c.1568C>T p.P523L missense 0.00001648●●●●●●
86. 67066471 c.1426G>A p.D476N missense 0.00001648●●●●●●
87. 67062006 c.730G>A p.V244I missense 0.00001647●●●●●●
88. 67047343 c.460A>G p.K154E missense 0.00001647●●●●●●
89. 67064639 c.1013G>A p.G338D missense 0.00001506●●●●●●
90. 67061880 c.604G>C p.E202Q missense 0.00000853●●●●●●
91. 67066495 c.1450G>C p.V484L missense 0.00000852●●●●●●
92. 67040539 c.169G>A p.A57T missense 0.00000851●●●●●●
93. 67049417 c.595A>T p.T199S missense 0.00000839●●●●●●
94. 67049411 c.589T>A p.C197S missense 0.00000835●●●●●●
95. 67066282 c.1237G>A p.G413R missense 0.00000834●●●●●●
96. 67061899 c.623A>G p.K208R missense 0.00000833●●●●●●
97. 67049334 c.512A>G p.E171G missense 0.00000833●●●●●●
98. 67040557 c.187C>A p.P63T missense 0.00000833●●●●●●
99. 67064843 c.1217C>T p.A406V missense 0.00000832●●●●●●
100. 67061901 c.625C>A p.Q209K missense 0.00000832●●●●●●
101. 67049402 c.580G>A p.E194K missense 0.00000831●●●●●●
102. 67064840 c.1214C>T p.A405V missense 0.00000831●●●●●●
103. 67040561 c.191C>T p.T64I missense 0.00000831●●●●●●
104. 67062462 c.848C>G p.T283S missense 0.00000830●●●●●●
105. 67064831 c.1205T>A p.L402Q missense 0.00000830●●●●●●
106. 67040563 c.193A>G p.R65G missense 0.00000830●●●●●●
107. 67066561 c.1516A>T p.T506S missense 0.00000830●●●●●●
108. 67064836 c.1210C>T p.P404S missense 0.00000830●●●●●●
109. 67049400 c.578T>A p.L193Q missense 0.00000830●●●●●●
110. 67062474 c.860A>T p.K287I missense 0.00000829●●●●●●
111. 67061910 c.634T>C p.C212R missense 0.00000829●●●●●●
112. 67064822 c.1196C>T p.P399L missense 0.00000829●●●●●●
113. 67064710 c.1084G>A p.V362I missense 0.00000828●●●●●●
114. 67066300 c.1255G>C p.G419R missense 0.00000828●●●●●●
115. 67049351 c.529G>A p.A177T missense 0.00000828●●●●●●
116. 67064819 c.1193C>A p.P398Q missense 0.00000828●●●●●●
117. 67064810 c.1184C>T p.S395F missense 0.00000828●●●●●●
118. 67064809 c.1183T>C p.S395P missense 0.00000828●●●●●●
119. 67066548 c.1503T>G p.S501R missense 0.00000827●●●●●●
120. 67064722 c.1096T>C p.F366L missense 0.00000827●●●●●●
121. 67064801 c.1175C>T p.P392L missense 0.00000827●●●●●●
122. 67040575 c.205A>G p.T69A missense 0.00000827●●●●●●
123. 67049354 c.532A>G p.I178V missense 0.00000827●●●●●●
124. 67049355 c.533T>C p.I178T missense 0.00000827●●●●●●
125. 67064764 c.1138T>C p.S380P missense 0.00000826●●●●●●
126. 67061929 c.653T>C p.L218P missense 0.00000826●●●●●●
127. 67066523 c.1478C>A p.A493E missense 0.00000826●●●●●●
128. 67066507 c.1462G>T p.A488S missense 0.00000826●●●●●●
129. 67064782 c.1156G>C p.A386P missense 0.00000826●●●●●●
130. 67066534 c.1489G>T p.G497C missense 0.00000826●●●●●●
131. 67064735 c.1109A>G p.D370G missense 0.00000826●●●●●●
132. 67066511 c.1466C>G p.A489G missense 0.00000826●●●●●●
133. 67066327 c.1282A>G p.T428A missense 0.00000826●●●●●●
134. 67064743 c.1117C>A p.P373T missense 0.00000826●●●●●●
135. 67066535 c.1490G>A p.G497D missense 0.00000826●●●●●●
136. 67066337 c.1292C>T p.P431L missense 0.00000825●●●●●●
137. 67062577 c.861A>C p.K287N missense 0.00000825●●●●●●
138. 67061932 c.656A>G p.Y219C missense 0.00000825●●●●●●
139. 67039670 c.167A>G p.Q56R missense 0.00000825●●●●●●
140. 67086811 c.1630A>C p.N544H missense 0.00000825●●●●●●
141. 67062578 c.862A>G p.I288V missense 0.00000825●●●●●●
142. 67040638 c.268C>A p.H90N missense 0.00000824●●●●●●
143. 67066427 c.1382C>T p.P461L missense 0.00000824●●●●●●
144. 67062028 c.752A>G p.Y251C missense 0.00000824●●●●●●
145. 67086757 c.1576G>A p.G526S missense 0.00000824●●●●●●
146. 67047341 c.458A>G p.H153R missense 0.00000824●●●●●●
147. 67039661 c.158A>G p.D53G missense 0.00000824●●●●●●
148. 67039573 c.70C>T p.L24F missense 0.00000824●●●●●●
149. 67040707 c.337A>G p.T113A missense 0.00000824●●●●●●
150. 67066484 c.1439G>A p.R480Q missense 0.00000824●●●●●●
151. 67047348 c.465C>G p.D155E missense 0.00000824●●●●●●
152. 67066475 c.1430C>T p.S477L missense 0.00000824●●●●●●
153. 67062070 c.794G>A p.G265E missense 0.00000824●●●●●●
154. 67062587 c.871G>A p.A291T missense 0.00000824●●●●●●
155. 67061980 c.704G>T p.R235L missense 0.00000824●●●●●●
156. 67062665 c.949G>A p.E317K missense 0.00000824●●●●●●
157. 67066376 c.1331G>A p.S444N missense 0.00000824●●●●●●
158. 67061988 c.712G>C p.E238Q missense 0.00000824●●●●●●
159. 67039609 c.106C>T p.P36S missense 0.00000824●●●●●●
160. 67066432 c.1387A>G p.S463G missense 0.00000824●●●●●●
161. 67062692 c.976T>C p.F326L missense 0.00000824●●●●●●
162. 67040658 c.288G>T p.Q96H missense 0.00000824●●●●●●
163. 67062033 c.757G>A p.D253N missense 0.00000824●●●●●●
164. 67062012 c.736G>A p.A246T missense 0.00000824●●●●●●
165. 67062641 c.925C>T p.H309Y missense 0.00000824●●●●●●
166. 67062022 c.746A>G p.K249R missense 0.00000824●●●●●●
167. 67047342 c.459C>G p.H153Q missense 0.00000824●●●●●●
168. 67066475 c.1430C>G p.S477W missense 0.00000824●●●●●●
169. 67039576 c.73A>C p.I25L missense 0.00000824●●●●●●
170. 67047254 c.371G>A p.C124Y missense 0.00000824●●●●●●
171. 67047241 c.358G>A p.D120N missense 0.00000824●●●●●●
172. 67066486 c.1441A>C p.K481Q missense 0.00000824●●●●●●
173. 67040623 c.253G>C p.V85L missense 0.00000824●●●●●●
174. 67066388 c.1343G>T p.G448V missense 0.00000824●●●●●●
175. 67062680 c.964C>T p.R322C missense 0.00000824●●●●●●
176. 67062596 c.880G>T p.A294S missense 0.00000824●●●●●●
177. 67061989 c.713A>C p.E238A missense 0.00000824●●●●●●
178. 67066402 c.1357G>T p.A453S missense 0.00000824●●●●●●
179. 67086724 c.1543C>T p.P515S missense 0.00000824●●●●●●
180. 67039645 c.142A>G p.R48G missense 0.00000824●●●●●●
181. 67047296 c.413A>G p.N138S missense 0.00000824●●●●●●
182. 67066438 c.1393G>A p.G465S missense 0.00000824●●●●●●
183. 67039556 c.53A>G p.D18G missense 0.00000824●●●●●●
184. 67040664 c.294C>A p.N98K missense 0.00000824●●●●●●
185. 67062643 c.927C>A p.H309Q missense 0.00000824●●●●●●
186. 67062051 c.775T>A p.S259T missense 0.00000824●●●●●●
187. 67040605 c.235C>G p.P79A missense 0.00000824●●●●●●
188. 67061943 c.667G>A p.E223K missense 0.00000824●●●●●●
189. 67086781 c.1600G>C p.A534P missense 0.00000824●●●●●●
190. 67086712 c.1531T>C p.F511L missense 0.00000824●●●●●●
191. 67066364 c.1319T>G p.L440W missense 0.00000824●●●●●●
192. 67066483 c.1438C>T p.R480W missense 0.00000824●●●●●●
193. 67039597 c.94A>T p.M32L missense 0.00000824●●●●●●
194. 67047256 c.373G>A p.E125K missense 0.00000824●●●●●●
195. 67047356 c.473T>C p.V158A missense 0.00000824●●●●●●
196. 67062010 c.734G>A p.R245H missense 0.00000824●●●●●●
197. 67047242 c.359A>T p.D120V missense 0.00000824●●●●●●
198. 67062082 c.806T>C p.M269T missense 0.00000824●●●●●●
199. 67066417 c.1372C>G p.P458A missense 0.00000824●●●●●●
200. 67062003 c.727C>T p.H243Y missense 0.00000824●●●●●●
201. 67066417 c.1372C>A p.P458T missense 0.00000824●●●●●●
202. 67062597 c.881C>T p.A294V missense 0.00000824●●●●●●
203. 67086734 c.1553G>C p.G518A missense 0.00000824●●●●●●
204. 67086734 c.1553G>A p.G518E missense 0.00000824●●●●●●
205. 67039646 c.143G>A p.R48K missense 0.00000824●●●●●●
206. 67047331 c.448T>A p.F150I missense 0.00000824●●●●●●
207. 67039655 c.152C>T p.A51V missense 0.00000824●●●●●●
208. 67040690 c.320T>A p.I107N missense 0.00000824●●●●●●
209. 67039563 c.60A>C p.L20F missense 0.00000824●●●●●●
210. 67062678 c.962T>C p.I321T missense 0.00000824●●●●●●
211. 67062054 c.778A>G p.K260E missense 0.00000824●●●●●●
212. 67039552 c.49A>G p.M17V missense 0.00000824●●●●●●
213. 67086785 c.1604G>A p.R535H missense 0.00000824●●●●●●
214. 67066369 c.1324T>C p.Y442H missense 0.00000824●●●●●●
215. 67047287 c.404A>G p.Y135C missense 0.00000824●●●●●●

* This highlights the relative frequency of the variant in the ExAC populations - Non-Finnish European, African, East Asian, South Asian, American and Finnish. Higher frequencies are denoted by darker shades of green, variants absent in a population are coloured light gray.

✝ Genomic coordinates refer to the GRCh37 release of the human genome.