Paralogue Annotation for KCNQ1 residue 434

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 434
Reference Amino Acid: G - Glycine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 434

No paralogue variants have been mapped to residue 434 for KCNQ1.



KCNQ1KLDKDNGV-------------------TP->G<EKMLTVPHITCDPPEERRL--------DHF456
KCNQ2-FSSPRGV-------------------AAK>G<KGSPQAQTVRRSPSADQSLED-SPSKVPKS483
KCNQ3RLSNPRGS-------------------NTK>G<KL--------FTPLNVDAIEE-SPSKEPKP463
KCNQ4RMGSSQRR-------------------TGP>S<KQHLAPPTMPTSPSSEQVGEATSPTKVQKS482
KCNQ5RMASPRGQ-------------------SIK>S<RQ--ASVGDRRSPSTDITAEG-SPTKVQKS464
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1LSETSSSK-------------------SFE>T<KEQGSPEK-------ARSSSSPQH-----L524
KCNB2LSETSSNK-------------------SFE>N<KYQEVSQKDSHEQLNNTSSSSPQH-----L535
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3------------------------------>-<------------------------------
KCNC4------------------------------>-<------------------------------
KCND1-------T-------------------CHE>-<----------------F------------T494
KCND2-------T-------------------NHE>-<----------------F------------V494
KCND3-------TGLSYLVDDPLLSVRTSTIKNHE>-<----------------F------------I511
KCNF1--IPLLTE---------------------->-<------------------------------482
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3--CNTTSL-------------------ENC>T<A-----------------------------490
KCNV1--W--------------------------->-<------------------------------499
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.G434Rc.1300G>A Putative BenignSIFT:
Polyphen: