Paralogue Annotation for KCNQ1 residue 463

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 463
Reference Amino Acid: S - Serine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 463

No paralogue variants have been mapped to residue 463 for KCNQ1.



KCNQ1PHITCDPPEERRL--------DHFSVDGYD>S<SVRKSPTLLEV---SM--------------476
KCNQ2QTVRRSPSADQSLED-SPSKVPKSW--SFG>D<RSRARQAF------RIKG------------500
KCNQ3----FTPLNVDAIEE-SPSKEPKPV--GLN>N<KERFRTAF------RMKA------------480
KCNQ4PTMPTSPSSEQVGEATSPTKVQKSW--SFN>D<RTRFRASL------RLK-------------498
KCNQ5VGDRRSPSTDITAEG-SPTKVQKSW--SFN>D<RTRFRPSL------RLKS------------481
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1EK-------ARSSSSPQH-----L------>-<--------NVQQLEDMYNKMAKTQ--SQPI544
KCNB2QKDSHEQLNNTSSSSPQH-----L------>-<--------SAQKLEMLYNEITKTQPHSHPN557
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3------------------------------>-<------------------------------
KCNC4------------------------------>-<------------------------------
KCND1----------F------------T------>-<--------DEL-------------------497
KCND2----------F------------V------>-<--------DEQ-------------------497
KCND3----------F------------I------>-<--------DEQ-------------------514
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.S463Tc.1388G>C Putative Benignrs184636161SIFT: tolerated
Polyphen: benign