Paralogue Annotation for KCNQ1 residue 481

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 481
Reference Amino Acid: R - Arginine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 481

No paralogue variants have been mapped to residue 481 for KCNQ1.



KCNQ1--------------------------PHFM>R<TN----------------SFAEDLDL----491
KCNQ2------------------------AASRQN>S<EE----------------ASLPGEDI----517
KCNQ3-------------------------YAFWQ>S<SE----------------DAGTGDPM----496
KCNQ4---------------------------PRT>S<AE----------------DA-PSEEV----511
KCNQ5------------------------QPKPVI>D<AD----------------TALGTDDV----499
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1SKPKEELEMESIPSPVAPLP-TRTEGVIDM>R<SMSSIDSFISCATDFPEATRFSHSP---LT610
KCNB2SAYEEEIEMEEVVCPQEQLAVAQTEVIVDM>K<STSSIDSFTSCATDFTETERSPLPPPSASH628
KCNC1------------------------------>-<-------------------CPHIDQA----525
KCNC2------------------------------>-<-------------------STGSEPP----551
KCNC3------------------------------>-<-------------------CPAIDQP----683
KCNC4------------------------------>-<-------------------GAGLTQP----561
KCND1------------------------TFSEAL>G<AV----------------SPGGRT-S----513
KCND2------------------------VFEESC>M<EV----------------ATVNRPSS----514
KCND3------------------------MFEQNC>M<ES----------------SMQNYPST----531
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.R481Ic.1442G>T Putative BenignSIFT:
Polyphen: