Paralogue Annotation for KCNQ1 residue 493

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 493
Reference Amino Acid: G - Glycine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 493

No paralogue variants have been mapped to residue 493 for KCNQ1.



KCNQ1-----------------------------E>G<ET----------------LLTPITHISQLR507
KCNQ2-----------------------------V>D<DK----------------SCPCEFVTEDLT533
KCNQ3-----------------------------A>E<DR----------------GYGNDFPIEDMI512
KCNQ4-----------------------------A>E<EK----------------SYQCELTVDDIM527
KCNQ5-----------------------------Y>D<EK----------------GCQCDVSVEDLT515
KCNA1------------------------------>-<--------------------TAN----CTT480
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<--------------------TAN----CTL484
KCNA3------------------------------>-<--------------------TAT----CTT558
KCNA4------------------------------>-<--------------------GDD----SET638
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<----------------------------P-516
KCNA7------------------------------>-<------------------------------
KCNB1GGSTAPEVGW-RGALGASGG----RF--VE>A<N-------PSPDASQHSSFFIESPKSSMKT663
KCNB2RGPPFLTLSREKGPAAR-DGTLEYAPVDIT>V<NLDASGSQCGLHSPLQSDNATDSPKSSLKG706
KCNC1------------------------------>-<------------------LTPDEGLPFTRS537
KCNC2------------------------------>-<------------------LSPPERLPIRRS563
KCNC3-----------------------------A>-<------------------MSPEDKSPIT-P695
KCNC4-----------------------------L>A<SS----------------PTPEERRALRRS577
KCND1-----------------------------R>S<TS----------------VSSQPVGPGSLL529
KCND2-----------------------------H>S<PS----------------LSSQQ----GVT526
KCND3-----------------------------R>S<PS----------------LSSHP----GLT543
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.G493Ac.1478G>C Putative BenignSIFT:
Polyphen: