Paralogue Annotation for KCNQ1 residue 544

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 544
Reference Amino Acid: Q - Glutamine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 544

No paralogue variants have been mapped to residue 544 for KCNQ1.



KCNQ1--------YFVAKKKFQQARKPYDVRDVIE>Q<YSQGHLNLMVRIKELQRRLDQSIGKPSLFI574
KCNQ2--------FLVSKRKFKESLRPYDVMDVIE>Q<YSAGHLDMLSRIKSLQSRVDQIVGRGPAIT600
KCNQ3--------FRLYKKKFKETLRPYDVKDVIE>Q<YSAGHLDMLSRIKYLQTRIDMIFTPGPPST579
KCNQ4--------FLVAKRKFKETLRPYDVKDVIE>Q<YSAGHLDMLGRIKSLQTRVDQIVGRGPGDR594
KCNQ5--------FHVAKRKFKETLRPYDVKDVIE>Q<YSAGHLDMLCRIKSLQTRVDQILGKGQITS582
KCNA1--------TD-------------------->-<------------------------------494
KCNA10--------SR-------------------->-<------------------------------510
KCNA2--------TD-------------------->-<------------------------------498
KCNA3--------TD-------------------->-<------------------------------574
KCNA4--------TD-------------------->-<------------------------------652
KCNA5LCLDTSRETD-------------------->-<------------------------------612
KCNA6--------TE-------------------->-<------------------------------528
KCNA7--------TE-------------------->-<------------------------------455
KCNB1--------EG-------DPSPLLPVLGMYH>D<PLRNRGSAAAAVAGLECA------------711
KCNB2--------ENRGSAPQTPPSTARPLPVTTA>D<FSLTTPQHISTILLEETP------------761
KCNC1--------LSTGEYACPPGGGMRK------>-<---DLCKESP---VIAKY------------576
KCNC2--------LTTGDYTCASDGGIRKG----Y>E<KSRSLNNIAGLAGNALRL------------614
KCNC3--------LT--DYAPSPDGSIRKATGAPP>L<PPQDWRKPGPPS-FLPDL------------747
KCNC4--------LSTGDYACA-DGSVRKG----T>F<VLRDLPLQHSP---EAAC------------624
KCND1--------LDMLA--GLRRSHAPQSRSSLN>A<KPHDSLDLNCDSRDFVAA------------597
KCND2--------LSTIQIRCVERTPLSNSRSSLN>A<KMEECVKLNCEQPYVTTA------------596
KCND3--------LSTIHIQGSEQPSLTTSRSSLN>L<KADDGLRPNCKTSQITTA------------613
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Gln544Leuc.1631A>T UnknownSIFT:
Polyphen: