Paralogue Annotation for KCNQ1 residue 574

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 574
Reference Amino Acid: I - Isoleucine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 574

No paralogue variants have been mapped to residue 574 for KCNQ1.



KCNQ1QYSQGHLNLMVRIKELQRRLDQSIGKPSLF>I<S-----------V-----------------576
KCNQ2QYSAGHLDMLSRIKSLQSRVDQIVGRGPAI>T<D--KDR--T--KG-----------------607
KCNQ3QYSAGHLDMLSRIKYLQTRIDMIFTPGPPS>T<P--KHKKSQKGSAFTFPSQQSPRNEPYVAR607
KCNQ4QYSAGHLDMLGRIKSLQTRVDQIVGRGPGD>R<KAREKG--D--KG-----------------603
KCNQ5QYSAGHLDMLCRIKSLQTRVDQILGKGQIT>S<D-KKSR--E--KI-----------------590
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1DPLRNRGSAAAAVAGLECA----------->-<------------------------------711
KCNB2DFSLTTPQHISTILLEETP----------->-<------------------------------761
KCNC1----DLCKESP---VIAKY----------->-<------------------------------576
KCNC2EKSRSLNNIAGLAGNALRL----------->-<------------------------------614
KCNC3LPPQDWRKPGPPS-FLPDL----------->-<------------------------------747
KCNC4FVLRDLPLQHSP---EAAC----------->-<------------------------------624
KCND1AKPHDSLDLNCDSRDFVAA----------->-<------------------------------597
KCND2AKMEECVKLNCEQPYVTTA----------->-<------------------------------596
KCND3LKADDGLRPNCKTSQITTA----------->-<------------------------------613
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.I574Vc.1720A>G Putative BenignSIFT:
Polyphen: