Paralogue Annotation for KCNQ1 residue 585

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 585
Reference Amino Acid: S - Serine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 585

No paralogue variants have been mapped to residue 585 for KCNQ1.



KCNQ1----V-----------------SEKSKDRG>S<NTIGARLNRVEDKVTQLDQRLALITDMLHQ615
KCNQ2T--KG-----------------PAEAELPE>D<PSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ646
KCNQ3QKGSAFTFPSQQSPRNEPYVARPSTSEI-E>D<QSMMGKFVKVERQVQDMGKKLDFLVDMHMQ645
KCNQ4D--KG-----------------PSDAEVVD>E<ISMMGRVVKVEKQVQSIEHKLDLLLGFYSR642
KCNQ5E--KI-----------------TAEHETTD>D<LSMLGRVVKVEKQVQSIESKLDCLLDIYQQ629
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1------------------------------>-<------------------------------
KCNB2------------------------------>-<------------------------------
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3------------------------------>-<------------------------------
KCNC4------------------------------>-<------------------------------
KCND1------------------------------>-<------------------------------
KCND2------------------------------>-<------------------------------
KCND3------------------------------>-<------------------------------
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.S585Nc.1754G>A Putative BenignSIFT:
Polyphen: