Paralogue Annotation for KCNQ1 residue 613

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 613
Reference Amino Acid: L - Leucine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 613

No paralogue variants have been mapped to residue 613 for KCNQ1.



KCNQ1RGSNTIGARLNRVEDKVTQLDQRLALITDM>L<HQLLSLHGGS----------------TPGS627
KCNQ2PEDPSMMGRLGKVEKQVLSMEKKLDFLVNI>Y<MQRMGIPPTE--TEAYFG--AKEPEPAPPY670
KCNQ3-EDQSMMGKFVKVERQVQDMGKKLDFLVDM>H<MQHMERLQVQ--VTE--------YYPTKGT663
KCNQ4VDEISMMGRVVKVEKQVQSIEHKLDLLLGF>Y<SRCLRSGTSA--SLGAVQVPLFDPDITSDY668
KCNQ5TDDLSMLGRVVKVEKQVQSIESKLDCLLDI>Y<QQVLRKGSASALALASFQIPPFECEQTSDY657
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1------------------------------>-<------------------------------
KCNB2------------------------------>-<------------------------------
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3------------------------------>-<------------------------------
KCNC4------------------------------>-<------------------------------
KCND1------------------------------>-<------------------------------
KCND2------------------------------>-<------------------------------
KCND3------------------------------>-<------------------------------
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.L613Fc.1837C>T Putative BenignSIFT:
Polyphen: