Paralogue Annotation for KCNQ1 residue 623

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 623
Reference Amino Acid: S - Serine
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 623

No paralogue variants have been mapped to residue 623 for KCNQ1.



KCNQ1NRVEDKVTQLDQRLALITDMLHQLLSLHGG>S<----------------TPGSGGPPREGG--635
KCNQ2GKVEKQVLSMEKKLDFLVNIYMQRMGIPPT>E<--TEAYFG--AKEPEPAPPYHSPEDSREH-679
KCNQ3VKVERQVQDMGKKLDFLVDMHMQHMERLQV>Q<--VTE--------YYPTKGTSSPAEAEK--671
KCNQ4VKVEKQVQSIEHKLDLLLGFYSRCLRSGTS>A<--SLGAVQVPLFDPDITSDYHSPVDHEDIS678
KCNQ5VKVEKQVQSIESKLDCLLDIYQQVLRKGSA>S<ALALASFQIPPFECEQTSDYQSPVDSKDLS667
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1------------------------------>-<------------------------------
KCNB2------------------------------>-<------------------------------
KCNC1------------------------------>-<------------------------------
KCNC2------------------------------>-<------------------------------
KCNC3------------------------------>-<------------------------------
KCNC4------------------------------>-<------------------------------
KCND1------------------------------>-<------------------------------
KCND2------------------------------>-<------------------------------
KCND3------------------------------>-<------------------------------
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.S623Ic.1868G>T Putative BenignSIFT:
Polyphen: