Paralogue Annotation for KCNQ1 residue 655

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 655
Reference Amino Acid: P - Proline
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 655

No paralogue variants have been mapped to residue 655 for KCNQ1.



KCNQ1-------------------------PELFL>P<S----NTLPTYEQLTVPRRGP-DEGS----676
KCNQ2TPGCR-PPEGNLRDSDTSISIPSVDHEELE>R<SFSGFSISQSKENLDALNSCY-AAVAPCAK829
KCNQ3RISPR-QRRSITRDSDTPLSLMSVNHEELE>R<SPSGFSISQDRDDYVFGPNGG-SS---WMR828
KCNQ4------------------------------>-<------------------------------
KCNQ5TKDRS-MRKSFDMGGETLLSVCPMVPKDLG>K<SLSVQNLIRSTEELNIQLSGS-ESSGSRGS857
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1SVDSS-PPK---SLPGSTSPKFSTG--TRS>E<KNHFESSPLPTSPKFLRQNCIYSTEAL-TG822
KCNB2AREEKQVD----SSPNCFADKPSDGRDPLR>E<EGSVGSSSPQDTGHNCRQDI-YHAVSE-VK875
KCNC1------------------------------>-<-----------------PTEA-VRV-----584
KCNC2------------------------------>-<-----------------PVTS-PYNSP---624
KCNC3------------------------------>-<-----------------ANAA-AWIS----756
KCNC4------------------------------>-<-----------------PTAG-TLFLP---634
KCND1SIPT--PPA---NT-----PDESQPSSPGG>G<GRAGSTLRNSSLGTPCLFPET-VKISS---646
KCND2SIPT--PPV---TT-----PE--------G>D<DRPE--SP------EYSGGNI-VRVSA---629
KCND3SIPT--PPA---LT-----PE--------G>E<SRPPPASPGPNTNIPSIASNV-VKVSA---654
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.P655Sc.1963C>T Putative BenignSIFT: deleterious
Polyphen: benign