Paralogue Annotation for KCNQ1 residue 660

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 660
Reference Amino Acid: P - Proline
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 660

No paralogue variants have been mapped to residue 660 for KCNQ1.



KCNQ1----------------PELFLPS----NTL>P<TYEQLTVPRRGP-DEGS-------------676
KCNQ2GNLRDSDTSISIPSVDHEELERSFSGFSIS>Q<SKENLDALNSCY-AAVAPCAK---------829
KCNQ3SITRDSDTPLSLMSVNHEELERSPSGFSIS>Q<DRDDYVFGPNGG-SS---WMR---------828
KCNQ4------------------------------>-<------------------------------
KCNQ5SFDMGGETLLSVCPMVPKDLGKSLSVQNLI>R<STEELNIQLSGS-ESSGSRGSQDFYPKWRE866
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1---SLPGSTSPKFSTG--TRSEKNHFESSP>L<PTSPKFLRQNCIYSTEAL-TGKGPSGQEKC831
KCNB2---SSPNCFADKPSDGRDPLREEGSVGSSS>P<QDTGHNCRQDI-YHAVSE-VKKD-SSQEGC883
KCNC1------------------------------>-<--------PTEA-VRV--------------584
KCNC2------------------------------>-<--------PVTS-PYNSP------------624
KCNC3------------------------------>-<--------ANAA-AWIS-------------756
KCNC4------------------------------>-<--------PTAG-TLFLP------------634
KCND1---NT-----PDESQPSSPGGGGRAGSTLR>N<SSLGTPCLFPET-VKISS------------646
KCND2---TT-----PE--------GDDRPE--SP>-<-----EYSGGNI-VRVSA------------629
KCND3---LT-----PE--------GESRPPPASP>G<PNTNIPSIASNV-VKVSA------------654
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.Pro660Hisc.1979C>A UnknownSIFT:
Polyphen: