Paralogue Annotation for KCNQ1 residue 672

Residue details

Gene: KCNQ1
Reference Sequences: LRG: LRG_287, Ensembl variant: ENST00000155840 / ENSP00000155840
Amino Acid Position: 672
Reference Amino Acid: P - Proline
Protein Domain: C-terminus


Paralogue Variants mapped to KCNQ1 residue 672

No paralogue variants have been mapped to residue 672 for KCNQ1.



KCNQ1----PELFLPS----NTLPTYEQLTVPRRG>P<-DEGS-------------------------676
KCNQ2PSVDHEELERSFSGFSISQSKENLDALNSC>Y<-AAVAPCAK---------VRPYIAEGES--839
KCNQ3MSVNHEELERSPSGFSISQDRDDYVFGPNG>G<-SS---WMR---------EKRYLAEGET--838
KCNQ4------------------------------>-<------------------------------
KCNQ5CPMVPKDLGKSLSVQNLIRSTEELNIQLSG>S<-ESSGSRGSQDFYPKWRESKLFITDEEVGP878
KCNA1------------------------------>-<------------------------------
KCNA10------------------------------>-<------------------------------
KCNA2------------------------------>-<------------------------------
KCNA3------------------------------>-<------------------------------
KCNA4------------------------------>-<------------------------------
KCNA5------------------------------>-<------------------------------
KCNA6------------------------------>-<------------------------------
KCNA7------------------------------>-<------------------------------
KCNB1FSTG--TRSEKNHFESSPLPTSPKFLRQNC>I<YSTEAL-TGKGPSGQEKC-----KL-----833
KCNB2PSDGRDPLREEGSVGSSSPQDTGHNCRQDI>-<YHAVSE-VKKD-SSQEGC-----KM-----885
KCNC1---------------------------PTE>A<-VRV--------------------------584
KCNC2---------------------------PVT>S<-PYNSP------------------------624
KCNC3---------------------------ANA>A<-AWIS-------------------------756
KCNC4---------------------------PTA>G<-TLFLP------------------------634
KCND1ESQPSSPGGGGRAGSTLRNSSLGTPCLFPE>T<-VKISS------------------------646
KCND2--------GDDRPE--SP------EYSGGN>I<-VRVSA------------------------629
KCND3--------GESRPPPASPGPNTNIPSIASN>V<-VKVSA------------------------654
KCNF1------------------------------>-<------------------------------
KCNG1------------------------------>-<------------------------------
KCNG2------------------------------>-<------------------------------
KCNG3------------------------------>-<------------------------------
KCNG4------------------------------>-<------------------------------
KCNS1------------------------------>-<------------------------------
KCNS2------------------------------>-<------------------------------
KCNS3------------------------------>-<------------------------------
KCNV1------------------------------>-<------------------------------
KCNV2------------------------------>-<------------------------------
cons                              > <                              

See full Alignment of Paralogues


Known Variants in KCNQ1

ProteinCDSDisease ClassificationDiseasedbSNP linksEffect Prediction
p.P672Tc.2014C>A Putative BenignSIFT: deleterious
Polyphen: benign